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Echocardiography in Pediatric and Adult Congenital Heart Disease (M - Medicine Ser.)
Par Benjamin W. Eidem, Frank Cetta. 2021
Edited by expert clinicians at Mayo Clinic and other leading global institutions, Echocardiography in Pediatric and Adult Congenital Heart Disease…
remains your reference of choice in this fast-changing field. The Third Edition brings you fully up to date not only with all aspects of pediatric echocardiography, but also with multimodality imaging in adult congenital heart disease, making it an invaluable resource for cardiologists, fellows, internists, and radiologists, as well as pediatric echocardiographers and sonographers."In The XX Brain, Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and…
mind, to ensure our brains remain resilient throughout our lives."--from the foreword by Maria ShriverThe first book to address cognitive enhancement and Alzheimer's prevention specifically in women--and to frame brain health as an essential component of Women's Health.In this revolutionary book, Dr. Lisa Mosconi, director of the Women's Brain Initiative at Weill Cornell Medical College, provides women with the first plan to address the unique risks of the female brain.Until now, medical research has focused on "bikini medicine," assuming that women are essentially men with breasts and tubes. Yet women are far more likely than men to suffer from anxiety, depression, migraines, brain injuries, and strokes. They are also twice as likely to end their lives suffering from Alzheimer's disease, even when their longer lifespans are taken into account. But in the past, the female brain has received astonishingly little attention and was rarely studied by medical researchers-- resulting in a wealth of misinformation about women's health.The XX Brain confronts this crisis by revealing how the two powerful X chromosomes that distinguish women from men impact the brain first and foremost and by focusing on a key brain-protective hormone: estrogen.Taking on all aspects of women's health, including brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances, and the increased risk of dementia, Dr. Mosconi introduces cutting-edge, evidence-based approaches to protecting the female brain, including a specific diet proven to work for women, strategies to reduce stress, and useful tips for restorative sleep. She also examines the controversy about soy and hormonal replacement therapy, takes on the perils of environmental toxins, and examines the role of our microbiome. Perhaps best of all, she makes clear that it is never too late to take care of yourself.The XX Brain is a rallying cry for women to have full access to information regarding what is going on in their brains and bodies as well as a roadmap for the path to optimal, lifelong brain health.How to Read a Paper: The Basics of Evidence-based Medicine and Healthcare (How To #22)
Par Trisha Greenhalgh. 2020
Required reading in many medical and healthcare institutions, How to Read a Paper is a clear and wide-ranging introduction to…
evidence-based medicine and healthcare, helping readers to understand its central principles, critically evaluate published data, and implement the results in practical settings. Author Trisha Greenhalgh guides readers through each fundamental step of inquiry, from searching the literature to assessing methodological quality and appraising statistics. How to Read a Paper addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. Now in its sixth edition, this informative text includes new and expanded discussions of study bias, political interference in published reports, medical statistics, big data and more. Offers user-friendly guidance on evidence-based healthcare that is applicable to both experienced and novice readers Authored by an internationally recognised practitioner and researcher in evidence-based healthcare and primary care Includes updated references, additional figures, improved checklists and more How to Read a Paper is an ideal resource for healthcare students, practitioners and anyone seeking an accessible introduction to evidence-based healthcare.Soft Tissue Injuries of the Head and Neck
Par Charilaos A. Ioannidis. 2023
This book provides a vividly illustrated description of a wide range of soft tissue injuries of the head and neck…
and their treatment, which forms part of the workload of both Plastic and Reconstructive Surgery and Cranio –Maxillofacial Surgery. Other medical and surgical disciplines are also involved, though to a lesser extent. It clarifies many topics, including the general principles of wound management, the treatment of various soft tissue injuries, burns, and wound healing disturbances.This book is intended for interns, residents and fellows of Plastic Surgery and Maxillofacial Surgery as well as surgeons and physicians of other disciplines dealing with soft tissue trauma of the head and neck. It may also prove useful to theatre and A & E nurses as well as medical students with interests in head and neck traumatology.Resource Scarcity in Austere Environments: An Ethical Examination of Triage and Medical Rules of Eligibility (Military and Humanitarian Health Ethics)
Par Sheena M. Eagan, Daniel Messelken. 2023
This book focuses on resource allocation in military and humanitarian medicine during times of scarcity and austerity. It is in…
these times that health systems bend, break, and even collapse and where resource allocation becomes a paramount concern and directly impacts clinical decision-making. Such times are challenging and this book covers this very important, yet, scarcely researched topic within the field of bioethics. This work brings together experts and practitioners in the fields of military health care, philosophy, ethics, and other disciplines to provide analysis on a variety of related topics ranging from case studies and first-hand experiences to policy and philosophical analysis. It is of great interest to to academics, practitioners, policy makers and students who are looking for analyses and guidance regarding the fair provision of medical care and the use of medical rules of eligibility under adverse conditions.Ergotherapie bei Demenzerkrankungen: Ein Förderprogramm
Par Gudrun Schaade. 2023
Der Band stellt ein praxiserprobtes Förderkonzept für die Arbeit mit an Demenz erkrankten Patienten vor und liefert zugleich notwendiges Grundlagenwissen.…
Insbesondere wird aufgezeigt, wie gängige rehabilitative Behandlungsansätze mit anderen Methoden kombiniert werden können, die speziell auf die Möglichkeiten von Demenz-Patienten abgestimmt sind. Handlungsanleitungen und ein umfangreicher Fundus an Übungsvorschlägen liefern Anregungen für die praktische Umsetzung. Geeignet als Einstiegslektüre für einen anspruchsvollen Aufgabenbereich.Sanctorius Sanctorius and the Origins of Health Measurement
Par Teresa Hollerbach. 2023
This open access book offers new insights into the Venetian physician Sanctorius Sanctorius (1561–1636) and into the origins of quantification…
in medicine. At the turn of the seventeenth century, Sanctorius developed instruments to measure and quantify physiological change. As trivial as the quantitative assessment of health issues might seem to us today – in times of fitness trackers and smart watches – it was highly innovative at that time. With his instruments, Sanctorius introduced quantitative research into the field of physiology. Historical accounts of Sanctorius and his work tend to tell the story of a genius who, almost out of the blue, invented a new medical science, based on measurement and quantification, that profoundly influenced modernity. Abandoning the “genius narrative,” this book examines Sanctorius and his work in the broader perspective of processes of knowledge transformation in early modern medicine. It is the first systematic study to include the entire range of the physician’s intellectual and practical activities. Adopting a material culture perspective, the research draws on the contemporary reconstruction of Sanctorius’s most famous instrument: the Sanctorian weighing chair. And here it departs from past studies that focus mainly on Sanctorius’s thinking rather than on his making and doing. The book also re-evaluates Sanctorius’s role in the wider process of the early transformation of medical culture in the early modern period, a process that ultimately led to the abandonment of Galenic medicine and to the introduction of a new medical science, based on the use of quantification and measurement in medical research. The book is therefore an important contribution to the history of medicine and historical epistemology aimed at historians of science and philosophy.Infectious Diseases Drug Delivery Systems
Par Ranjita Shegokar, Yashwant Pathak. 2023
The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as…
an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future.A total of four books are covered under the series of Infectious drug diseases.- Malarial drug delivery systems- Tubercular drug delivery systems- Viral drug delivery systems- Infectious disease drug delivery systemsInfectious diseases are the world’s greatest killers that present one of the most significant health and security challenges. Humans have lived with emerging and re-emerging pathogens since before the documented history of civilization. The only determining fact today is - If the situation is “worse” or “better” than in past. The answer is probably “worse”, may be due significant increase in human population, increased cross-continent mobility, imbalanced (stressed) life style, irregular food habits leading to compromised innate immunity and over or under practiced hygiene routine. When the incidence of such a disease in people increases over 20 years or threatens to increase, it is called an “emerging” disease, and a growing number have made watch lists and headlines in nearly every country -like highly pathogenic H5N1 avian influenza, severe acute respiratory syndrome (SARS), Ebola virus, food- and waterborne illnesses, and a range of antimicrobial-resistant bacterial diseases TB. This book addresses current and new therapy developments in treating such infectious diseases, updates on finding new drugs, identification of innovative diagnostic methods, understanding of disease research models and clinical trials performances of new treatment modalities.Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of infectious diseases and related research.Medical Persuasion: Understanding the Impact on Medical Argumentation
Par Vic Velanovich. 2023
This unique book is a major contribution to the literature on persuasion in communication, and on doctor-patient communication, in particular. …
Written by a physician-scientist with deep experience on the topic, the book offers a comprehensive analysis of what makes an argument in medicine persuasive, outlining the characteristics of an argument that causes people to accept that the conclusion(s) of an argument are true. Although the book focuses on medical arguments in particular, the general approach offered by the author is appropriate for any informal argument. The central emphasis is that although sound logical construction and true premises are required to establish the logical truth of a conclusion, this is insufficient for persuasion to occur. Although formal logic can exist independent of human reception, real-world arguments must have both an arguer (the individual constructing the argument) and an audience (individuals listening and evaluating the argument). Whether the audience is capable of changing their world view is as important as the logical construction of the argument, maintains the author. To illustrate all points, a plethora of examples in medical research and in diagnosis and treatment decisions are presented. Medical Persuasion: Understanding the Impact on Medical Argumentation is a unique contribution to the clinical literature and will be of immense interest to medical practitioners, researchers, and philosophers as a way of gaining insights into constructing arguments for their peers and patients. In addition, medical trainees will gain important insights in the production of medical knowledge and medical practices, and even students in the social sciences and humanities will find the work valuable as a conduit to gaining insight into the reception of an argument.Understanding Brain Disease
Par Joseph B. Martin. 2005
Understanding Brain Diseaseis as much for the specialist as it is for the lay person interested in finding out…
where we are today in the scientific attempts to understand and control such conditions as stroke, Alzheimer’s, Parkinson’s, and BSE. The book will help build bridges between medical practitioners and researchers and the general public. One has only to take stock of Canadian statistics to realize the immense, and world-wide, significance of this research and the need for information -- Stroke is the fourth leading cause of death in Canada. Each year, about 16,000 Canadians die from stroke. Each year, more women than men die from stroke. There are between 40,000 and 50,000 strokes in Canada each year. For every 10,000 Canadian children under the age of 19, there are 6. 7 strokes. About 300,000 Canadians are living with the effects of stroke. After age 55, theriskof stroke doubles every 10 years. A stroke survivor has a 20% chance of having another stroke within 2 years. Of every 100 people who have a stroke 15 die (15%) 10 recover completely (10%) 25 recover with a minor impairment or disability (25%) 40 are left with a moderate to severe impairment (40%) 10 are so severely disabled they require long-term care (10%) Stroke costs the Canadian economy $2. 7 billion a year. The average acute care costs is about $27,500 per stroke. Canadians spend a total of 3 million days in hospital because of stroke. - Heart & Stroke Foundation of Canada StatisticsThe Exhaustion Breakthrough: Unmask the Hidden Reasons You're Tired and Beat Fatigue for Good
Par Holly Phillips. 2015
It's become the norm to complain that we're always tired. In Dr. Holly Phi llips' Exhaustion Solution, Dr. Holly aims…
to end this accepted state of exhaustion and send a message to readers that they do not have to be drained of energy just because they have a demanding job, a family, or an active social life—or all three. She also explains the insidious nature of fatigue, educating readers on the havoc that persistent tiredness wreaks on the body and mind, from weight gain and cognitive impairment to even a higher risk of heart attack and stroke.Dr. Holly's passion for the subject stems from the quest to cure her own constant weariness—which she struggled with for more than 20 years—as well as the countless complaints of chronic tiredness she hears from patients each day in her internal medicine practice. While a few readers might find a link between their fatigue and a medical condition such as chronic fatigue syndrome or fibromyalgia, Dr. Holly knows that many more will discover that diet, exercise, and sleep habits are contributing to their lack of energy.This guide will help readers understand their exhaustion, rule out any underlying illnesses, correct any allergies or hormonal issues that may be contributing to extreme tiredness, and incorporate lifestyle factors and alternative therapies that will improve overall energy. Clear, comprehensive, and practical, Dr. Holly Phillips' Exhaustion Solution shines a bright light on an issue many people have simply accepted—but that they don't have to any longer.The Paper Office for the Digital Age: Forms, Guidelines, and Resources To Make Your Practice Work Ethically, Legally, and Profitably
Par Edward L. Zuckerman, Keely Kolmes. 2017
Significantly revised and updated to include online and computerized aspects of private practice, this essential manual has given many tens…
of thousands of clinicians the complete record-keeping and risk-reduction tools that every psychotherapy practice needs. The book provides effective methods for obtaining informed consent, planning treatment and documenting progress, managing HIPAA compliance, maintaining clinical and financial records, communicating with clients and third-party payers, and reducing malpractice risk. Drawing from the professional literature, it features key guidance and easy-to-digest pointers about the ethical, legal, and business aspects of practice. With a large-size format for easy photocopying, the book and enclosed CD-ROM include 53 reproducible forms and handouts. Purchasers also get access to a companion website where they can download and customize the reproducible materials. New to This Edition: *Updated throughout to reflect today's greater use of electronic/digital technologies in practice management. *Chapter on insurance and billing, coping with managed care, and Medicare. *Chapter on private practice marketing, including Internet and social media dos and don'ts. *Expanded topics: HIPAA compliance, ICD-10, responding to subpoenas, and using online technologies for billing, communication, and record keeping. *Information about hundreds of websites dealing with all aspects of operating a practice. See also Clinician's Thesaurus, 8th Edition, by Edward L. Zuckerman, the indispensable resource for conducting interviews and writing psychological reports.Estimation of the Time Since Death
Par Burkhard Madea. 2023
Estimation of the Time Since Death remains the foremost authoritative book on scientifically calculating the estimated time of death postmortem.…
Building on the success of previous editions which covered both the early and later postmortem periods this edition includes a new chapter on DNA/RNA degradation and further new content on drug testing in hair, thus widening the scope of the material. Chapters have been improved, updated and expanded, and include new and additional images to enhance the text. A unique work of synthesis combining rigorous science with practical guidance, this update reinforces the book’s reputation as an invaluable resource – and also the standard – for the estimation of the time since death.Sample Sizes for Clinical Trials
Par Steven A. Julious. 2023
Sample Sizes for Clinical Trials, Second Edition is a practical book that assists researchers in their estimation of the sample…
size for clinical trials. Throughout the book there are detailed worked examples to illustrate both how to do the calculations and how to present them to colleagues or in protocols. The book also highlights some of the pitfalls in calculations as well as the key steps that lead to the final sample size calculation. Features: Comprehensive coverage of sample size calculations, including Normal, binary, ordinal, and survival outcome data Covers superiority, equivalence, non-inferiority, bioequivalence and precision objectives for both parallel group and crossover designs Highlights how trial objectives impact the study design with respect to both the derivation of sample formulae and the size of the study Motivated with examples of real-life clinical trials showing how the calculations can be applied New edition is extended with all chapters revised, some substantially, and four completely new chapters on multiplicity, cluster trials, pilot studies, and single arm trials The book is primarily aimed at researchers and practitioners of clinical trials and biostatistics, and could be used to teach a course on sample size calculations. The importance of a sample size calculation when designing a clinical trial is highlighted in the book. It enables readers to quickly find an appropriate sample size formula, with an associated worked example, complemented by tables to assist in the calculations.Basic and Translational Applications of the Network Theory for Dystonia (Advances in Neurobiology #31)
Par Aasef Shaikh, Anna Sadnicka. 2023
A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network. Impairment in any of…
the “nodes” of the network may result in deficient network activity, causing dystonia. This book aims to present various experimental evidence supporting the network theory of dystonia. Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations. Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia. Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting. With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder. This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation (Progress in Inflammation Research #87)
Par Carlo Rossetti, Francesco Peri. 2021
TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways…
in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer’s diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis and neuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.Inflammation and Epilepsy: New Vistas (Progress in Inflammation Research #88)
Par Damir Janigro, Astrid Nehlig, Nicola Marchi. 2021
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy…
as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.Getting to Know Your Cells
Par Leslie Saucedo. 2023
This book acts as a field-guide for human cells. The book’s unique structure first separates cells by what makes them…
distinctive, and then examines the essential “tools and parts” needed for both the cells’ specialized function, and also the basic mechanisms that are shared with most other cells. The chapters highlight interactions between multiple cell types, exploring areas such as immunology and cancer to exemplify the complex coordination of cells, as well as the manipulation of normal cell interactions. This book works as a companion reference for an academic text in cell and molecular science, and will be of general interest to anyone who wants to learn more about how cells work and interact.This open access book maps a crucial but neglected chapter in the history of psychiatry: how was melancholia transformed in…
the nineteenth century from traditional melancholy madness into a modern biomedical mood disorder, paving the way for the emergence of clinical depression as a psychiatric illness in the twentieth century? At a time when the prevalence of mood disorders and antidepressant consumption are at an all-time high, the need for a comprehensive historical understanding of how modern depressive illness came into being has never been more urgent. This book addresses a significant gap in existing scholarly literature on melancholia, depression, and mood disorders by offering a contextualised and critical perspective on the history of melancholia in the first decades of psychiatry, from the 1830s until the turn of the twentieth century.Point-of-Care Biosensors for Infectious Diseases
Par Sushma Dave, Jayashankar Das. 2023
Point-of-Care Biosensors for Infectious Diseases Comprehensive resource covering key developments in biosensor-based diagnostics for infectious diseases With its overview of…
currently available technologies, Point-of-Care Biosensors for Infectious Diseases serves as a starting point for the successful development and application of pathogen biosensors in a point-of-care setting. Here, expert authors review current challenges in pathogen detection and the selection of suitable biomarkers, detail currently available biosensor platforms including electrochemical, piezoelectric, magnetic, and optical sensors, and cover technology development for point-of-care biosensors for viral, bacterial, and parasitic infections. Point-of-Care Biosensors for Infectious Diseases covers key topics such as: Fundamentals of biosensor detection, with a focus on optical and electrochemical techniques Organic and inorganic based nanomaterials for healthcare diagnostics Strategies for miniaturizing biosensor devices, and state-of-the-art integrated sensing platforms Latest trends in point-of-care biosensing systems to detect, diagnose, and monitor infectious diseases Providing comprehensive coverage of the subject, Point-of-Care Biosensors for Infectious Diseases is an excellent reference for all developers, researchers, and technology managers in the areas of molecular diagnosis, infectious diseases, biosensors, and related fields.