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Kisspeptin Signaling in Reproductive Biology
Par Jeremy T. Smith, Alexander S. Kauffman. 2013
Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later…
in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.Dementia, Culture and Ethnicity: Issues for All
Par Jan Smith, Sofia Laura Escudero, Jo Moriarty, Shemain Wahab, Vincent Goodorally, Joy Watkins, Karen Jutlla, Ajit Shah, Jill Manthorpe, Karen Harrison Dening, Omar Khan, Alisoun Milne, Alistair Burns, Julia Botsford. 2015
With contributions from experienced dementia practitioners and care researchers, this book examines the impact of culture and ethnicity on the…
experience of dementia and on the provision of support and services, both in general terms and in relation to specific minority ethnic communities. Drawing together evidence-based research and expert practitioners' experiences, this book highlights the ways that dementia care services will need to develop in order to ensure that provision is culturally appropriate for an increasingly diverse older population. The book examines cultural issues in terms of assessment and engagement with people with dementia, challenges for care homes, and issues for supporting families from diverse ethnic backgrounds in relation to planning end of life care and bereavement. First-hand accounts of living with dementia from a range of cultural and ethnic backgrounds give unique perspectives into different attitudes to dementia and dementia care. The contributors also examine recent policy and strategy on dementia care and the implications for working with culture and ethnicity. This comprehensive and timely book is essential reading for dementia care practitioners, researchers and policy makers.Sleep Loss and Obesity
Par Tamas Horvath, Priyattam Shiromani, Susan Redline, Eve Van Cauter. 2012
Sleep Loss and Obesity: Intersecting Epidemics represents a major contribution to the field of sleep medicine. It is a comprehensive…
review of the neurobiology of sleep, circadian timing and obesity, the deleterious effects of sleep loss and obesity on health, and the worrisome associated social and medical costs in a range of patient populations and overall to society. The number of individuals who are obese has reached alarming levels. As a result, the incidence of Type 2 diabetes, cardiovascular disorders, heart disease, and kidney failure have also increased. The surgeon general estimates that the total annual cost of obesity in the US is about $117 billion. This cost is expected to escalate significantly because the number of overweight and obese children is increasing rapidly. Indeed, the new generation is expected to have a shorter life-span then their parents. In addition, sleep loss is emerging as an important contributing factor to obesity. People who sleep less or are sleep deprived tend to eat more, especially carbohydrates, and have a higher body mass index. Increased weight restricts the upper airway, causing obstructive sleep apnea and further sleep loss. In the end there is a vicious cycle of weight gain and sleep loss. In the past few years there has been a tremendous growth in our understanding of brain mechanisms controlling energy metabolism. Interestingly the neurons regulating waking also regulate feeding. There is also a mechanism that regulates the timing of feeding and sleep. In shift-workers this system is likely to be disturbed, and this has an adverse impact on both feeding and sleep. Sleep Loss and Obesity: Intersecting Epidemics is the first title to clearly examine how obesity and sleep loss are interacting epidemics. This fascinating title makes the link between energy metabolism, sleep and circadian timing; identifies poor sleep as a risk-factor for obesity in children and adults and offers treatment strategies for obstructive sleep apnea and obesity. This book will be a vital source of information for all physicians interested in sleep disorders and obesity. It will also be of value to neuroscientists, health system administrators, and policy makers.Aging and Diversity
Par Stephen Fried, Lisa S. Wagner, Chandra M. Mehrotra. 2009
This new edition has been completely rewritten and includes chapters that address key topics in diversity and aging: research methods,…
psychological aging; health beliefs, behaviors, and services; health disparities; informal and formal care for older persons; work and retirement; religious affiliation and spirituality; and death, dying, and bereavement. Taking a broad view of diversity, Mehrotra and Wagner discuss elements of diversity such as gender, race or ethnicity, religious affiliation, social class, rural-urban community location and sexual orientation. Including these elements allows them to convey some of the rich complexities of our diverse culture - complexities that provide both challenges to meet the needs of diverse population and opportunities to learn how to live in a pluralistic society. Throughout the book, Mehrotra and Wagner present up-to-date knowledge and scholarship in a way that engages readers in active learning. Rather than simply transmitting information, the authors place ongoing emphasis on developing readers' knowledge and skills; fostering higher order thinking and encouraging exploration of personal values and attitudes. Distinctive features of the book include: Opening vignettes for each chapter that present a sampling of how the issues to be discussed apply to diverse elders. Active learning experiences that invite readers to interview diverse elders, conduct internet searches, and give an analysis of a case study. Quizzes at the end of the chapters help readers ascertain the extent to which they have learned the material; the key for each quiz includes details about correct and incorrect responses so that additional learning can occur. Aging and Diversity Online boxes interspersed throughout the book provide internet resources that readers may use to find new research and publications. Suggested readings and audiovisual resources given at the end of each chapter serve as a guide to additional information on topics covered in the chapter. This approach of presenting the material will help the readers understand and apply key concepts and principles in ways that will not only improve the lives of older people they serve, but will also enhance their own aging experience.The Everything Guide to Managing Type 2 Diabetes
Par Paula Ford-Martin, Jason Baker. 2012
Diabetes is a complex disease--but learning about it shouldn't be! A Type 2 diabetes diagnosis can be daunting, but it…
is also manageable. With this all-in-one guide, you will get expert advice on establishing a healthier lifestyle and getting control of your diabetes. The Everything Guide to Managing Type 2 Diabetes provides easy-to-follow advice on all aspects of living with diabetes, and helps you: Recognize the symptoms of prediabetes and diabetes Monitor your blood glucose levels Learn about the types of insulin and insulin-delivery systems Understand the importance of nutrition and exercise Reduce the short- and long-term effects of diabetes Filled with reliable advice and the latest information on medication, therapies, blood sugar monitoring, and more, this invaluable guide shows you how to take control of your diabetes and enjoy your life!Darwinian medicine looks at the ecological and evolutionary roots of disease. A disease is an interaction between a genome and…
its biotic or abiotic environment and therefore a disease is essentially an ecological process. Good understanding of ecology and a Darwinian way of thinking can give us novel and useful perspectives on health and disease. If we understand the disease process better, we can certainly prevent, control as well as treat diseases in a better way. Although the thought that the origins of obesity and type 2 diabetes (T2D) might lie in our hunter gatherer adaptations is not new, research over the last decade makes us rethink many of the classical concepts. Brain and behavior is increasingly being recognized as central to all the endocrine, metabolic and immunological changes that earmark type 2 diabetes and other metabolic syndrome disorders. A major change in paradigm appears to be on the horizon and the proposed book intends to speed up the paradigm shift by raising important questions, pointing out flaws and inadequacies in the prevalent paradigm and stimulating radical rethinking which would redirect and refine the line of research as well as bring some fundamental changes in drug discovery and clinical practice.Abuse and Neglect of the Elderly in India
Par S. Irudaya Rajan, Mala Kapur Shankardass. 2018
This book highlights different aspects of the problem of elder abuse and neglect in India and discusses its forms…
as well as means of prevention intervention and management It presents a framework for understanding the occurrence of elder abuse and neglect in India placing the discussion within the global context Elder abuse and neglect is a growing concern in South Asia and this is the first comprehensive account of the topic from India It uses data from different parts of India to describe the various dimensions of elder abuse and neglect among different population categories and sections in society Covering rural and urban areas in different states it discusses current perspectives on elder abuse and neglect at the household level widows HIV-affected populations and those residing in institutions This book comprises views from experts in the field and is of interest to researchers and academics from the social and behavioural sciences policy makers and NGOsRetirement On The Line: Age, Work, and Value in an American Factory
Par Caitrin Lynch. 2007
In an era when people live longer and want (or need) to work past the traditional retirement age, the Vita…
Needle Company of Needham, Massachusetts provides inspiration and important lessons about the value of older workers. Vita Needle is a family-owned factory that was founded in 1932 and makes needles, stainless steel tubing and pipes, and custom fabricated parts. As part of its unusual business model, the company seeks out older workers; the median age of the employees is seventy-four. In Retirement on the Line, Caitrin Lynch explores what this unusual company's commitment to an elderly workforce means for the employer, the workers, the community, and society more generally. Benefiting from nearly five years of fieldwork at Vita Needle, Lynch offers an intimate portrait of the people who work there, a nuanced explanation of the company's hiring practices, and a cogent analysis of how the workers' experiences can inform our understanding of aging and work in the twenty-first century. As an in-depth study of a singular workplace, rooted in the unique insights of an anthropologist who specializes in the world of work, this book provides a sustained focus on values and meanings-with profound consequences for the broader assumptions our society has about aging and employment.Atlas of Lymphatic Anatomy in the Head, Neck, Chest and Limbs
Par Wei-Ren Pan. 2017
This atlas provides detailed information on the human lymphatic system in the head neck and chest regions as well…
as the extremities with more than 400 photographs and radiographs including micro and macro views of the morphology Much of the content is presented for the first time such as the individual differences in lymphatic distribution especially in the head neck region characteristics of the indirect precollecting lymph vessel in the scalp the lymphatic ampulla and diverticulum and the transparent lymph node Providing insights into the lymphatic anatomy the book is an essential resource for medical and science students as well as therapists clinicians and researchers working in this fieldThe Mini-Fast Diet: Burn Fat Faster Than Ever with the Simple Science of Intermittent Fasting
Par Peggy Dace, Julian Whitaker. 2013
In this breakthrough plan by a renowned wellness doctor, one simple lifestyle change can help reverse metabolic syndrome, drop pounds,…
and lower insulin levels and blood pressure. The magic secret? A clinically proven, research-backed mini-fast that drives the body into an extreme fat-burning state called ketosis. Just skip breakfast, then add a simple exercise program to burn even more fat. After the mini-fast, eat normally for the rest of the day, focusing on proper portions of lean protein, vegetables, and low-fat, low-glycemic carbs. No counting calories—and no hunger. Readers will learn everything they need to follow this expertly designed program, plus: • How to kickstart and stay in ketosis • A 2-week sample meal plan with more than 50 easy, delicious recipes • Advice on safe, effective exercise habits, plus an illustrated guide to the fitness plan • Success stories from people who have changed their lives with the diet • Science on how the program helps fight or prevent diabetes, arthritis, heart disease, and moreBalancing Diabetes
Par Kerri Sparling. 2014
When a person receives a diagnosis of diabetes, he or she starts a process of adjusting and making sense of…
the new normal living with a chronic disease. A large part of that adjustment is figuring out how to balance diabetes with all the intricacies of a life outside of diabetes care. In Balancing Diabetes, diabetes online community blogger Kerri Sparling compiles strategies used by people with diabetes and their caregivers to bring that elusive balance into their lives. Whether adult or child, type 1 or type 2, spouse or caregiver, male or female, people in the diabetes world will find themselves in this book and be inspired by the commonality of that continuing search for balance.When I'm 64
Par National Research Council of the National Academies. 2006
By 2030 there will be about 70 million people in the United States who are older than 64. Approximately 26…
percent of these will be racial and ethnic minorities. Overall, the older population will be more diverse and better educated than their earlier cohorts. The range of late-life outcomes is very dramatic with old age being a significantly different experience for financially secure and well-educated people than for poor and uneducated people. The early mission of behavioral science research focused on identifying problems of older adults, such as isolation, caregiving, and dementia. Today, the field of gerontology is more interdisciplinary. When I'm 64 examines how individual and social behavior play a role in understanding diverse outcomes in old age. It also explores the implications of an aging workforce on the economy. The book recommends that the National Institute on Aging focus its research support in social, personality, and life-span psychology in four areas: motivation and behavioral change; socioemotional influences on decision-making; the influence of social engagement on cognition; and the effects of stereotypes on self and others. When I'm 64 is a useful resource for policymakers, researchers and medical professionals.Working with Older People (The Social Work Skills Series)
Par John Harris, Denise Tanner. 2008
Working with older people has become an increasingly important part of social work education and practice. Whether studying community care,…
adult services, human growth and development, or social work processes and interventions, this book will be a vital source of information and help. Working with Older People provides a framework of knowledge, skills and values pertinent to qualifying social work courses and the new post-qualifying award in Social Work with Adults, including discussion of: ideas about human development and theories of older age legislation, social policy and social welfare skills for working with older people assessment and care planning partnership working. Written by two experienced educators and practitioners, this key text facilitates individual or group learning through features such as objectives for each chapter, case studies and further reading suggestions. There are numerous activities throughout the book and the final chapter contains pointers to consider for all of the activities. It will be essential reading for social work students and qualified social workers.Frontiers in Gynecological Endocrinology
Par Bart C J M Fauser. 2015
This volume offers an up-to-date overview on the major areas of gynecological endocrinology presenting the latest advances in adolescent…
gynecological endocrinology assisted reproduction menstrual-related disorders sexuality and transsexualism polycystic ovary syndrome myometrial pathology and adenomyosis obesity and metabolic syndrome hormonal contraception premature ovarian failure and menopause In each chapter the recent advances deriving from basic science and clinical investigations are related to the practical management of the condition under consideration taking into account the need for individualized therapies The book is published within the ISGE Book Series a joint venture between the International Society of Gynecological Endocrinology and Springer and is based on the 2014 International School of Gynecological and Reproductive Endocrinology Winter Course It will be an important tool for obstetricians and gynecologists endocrinologists and experts in women s health as well as interested GPsPreparing For An Aging World: The Case For Cross-national Research
Par National Research Council. 2001
Aging is a process that encompasses virtually all aspects of life. Because the speed of population aging is accelerating, and…
because the data needed to study the aging process are complex and expensive to obtain, it is imperative that countries coordinate their research efforts to reap the most benefits from this important information. Preparing for an Aging World looks at the behavioral and socioeconomic aspects of aging, and focuses on work, retirement, and pensions; wealth and savings behavior; health and disability; intergenerational transfers; and concepts of well-being. It makes recommendations for a collection of new, cross-national data on aging populations—data that will allow nations to develop policies and programs for addressing the major shifts in population age structure now occurring. These efforts, if made internationally, would advance our understanding of the aging process around the world.Technology For Adaptive Aging
Par National Research Council of the National Academies. 2004
Emerging and currently available technologies offer great promise for helping older adults, even those without serious disabilities, to live healthy,…
comfortable, and productive lives. What technologies offer the most potential benefit? What challenges must be overcome, what problems must be solved, for this promise to be fulfilled? How can federal agencies like the National Institute on Aging best use their resources to support the translation from laboratory findings to useful, marketable products and services? Technology for Adaptive Aging is the product of a workshop that brought together distinguished experts in aging research and in technology to discuss applications of technology to communication, education and learning, employment, health, living environments, and transportation for older adults. It includes all of the workshop papers and the report of the committee that organized the workshop. The committee report synthesizes and evaluates the points made in the workshop papers and recommends priorities for federal support of translational research in technology for older adults.Genes, Behavior, and the Social Environment: Moving Beyond the Nature/Nurture Debate
Par Institute of Medicine of the National Academies. 2006
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public…
health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.Understanding Racial And Ethnic Differences In Health In Late Life: A Research Agenda
Par Panel On Race, Ethnicity, Health in Later Life. 2004
As the population of older Americans grows, it is becoming more racially and ethnically diverse. Differences in health by racial…
and ethnic status could be increasingly consequential for health policy and programs. Such differences are are not simply a matter of education or ability to pay for health care. For instance, Asian Americans and Hispanics appear to be in better health, on a number of indicators, than White Americans, despite, on average, lower socioeconomic status. The reasons are complex, including possible roles for such factors as selective migration, risk behaviors, exposure to various stressors, patient attitudes, and geographic variation in health care. This volume, produced by a multidisciplinary panel, considers such possible explanations for racial and ethnic health differentials within an integrated framework. It provides a concise summary of available research and lays out a research agenda to address the many uncertainties in current knowledge. It recommends, for instance, looking at health differentials across the life course and deciphering the links between factors presumably producing differentials and biopsychosocial mechanisms that lead to impaired health.Developments in the Economics of Aging
Par David A. Wise. 2009
The number of Americans eligible to receive Social Security benefits will increase from forty-five million to nearly eighty million in…
the next twenty years. Retirement systems must therefore adapt to meet the demands of the largest aging population in our nation's history. In Developments in the Economics of Aging, David A. Wise and a distinguished group of analysts examine the economic issues that will confront policy makers as they seek to design policies to protect the economic and physical health of these older Americans. The volume looks at such topics as factors influencing work and retirement decisions at older ages, changes in life satisfaction associated with retirement, and the shift in responsibility for managing retirement assets from professional money managers of traditional pension plans to individual account holders of 401(k)s. Developments in the Economics of Aging also addresses the complicated relationship between health and economic status, including why health behaviors vary across populations and how socioeconomic measures correlate with health outcomes.Vigil
Par Morris Panych. 2012
A man returns after thirty years to sit with a relative on her deathbed. Kemp's problem is: she's not dying…
fast enough. Through Kemp's own errors and inattentiveness, the visit that he thinks will take a day or two stretches into a year. A play of mistaken identity, twisted circumstance, and surprising turns, this is one Vigil worth keeping.