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Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis
Par Robert A. Copeland. 2023
ENZYMES A complete and approachable introduction to the study of enzymes, from theory to practice Enzymes catalyze the bulk of…
important biological processes, both metabolic and biochemical. They are specialized proteins whose function is determined by their structure, understanding which is therefore a key focus of biological, pharmacological, and agrarian research, among many others. A thorough knowledge of enzyme structure, pathways, and mechanisms is a fundamental building block of the life sciences and all others connected to them. Enzymes offers a detailed introduction to this critical subject. It analyzes enzyme proteins at the structural level and details the mechanisms by which they perform their catalyzing functions. The book’s in-depth engagement with primary literature and up-to-date research allows it to continuously deploy illustrative examples and connect readers with further research on key subjects. Fully updated after decades as the standard text, this book unlocks a thriving field of biological and biochemical research. Readers of the third edition of Enzymes will also find: Expanded chapters on steady-state and transient-state enzyme kinetics, structural components of enzymes, and more New chapters on enzyme regulation, enzyme-macromolecule interactions, enzyme evolution, and enzymes in human health Key Learning Points at the beginning of each chapter to assist students and instructors Enzymes promises to continue as the standard reference on this subject for practitioners of the life sciences and related fields in both academia and industry.The Disabled Body in Contemporary Art
Par Ann Millett-Gallant. 2024
The second edition offers an essential update to the foundational first edition, The Disabled Body in Contemporary Art. Featuring updated chapters…
and case studies, this second edition will not only expand on the first edition but will bring a new focus to contemporary disabled artists and their embodied, multimedia work.Essential Clinical Global Health (Essentials)
Par Brett D. Nelson. 2015
Essential Clinical Global Health is a brand-new, pioneering, and evidence-based textbook that provides a clinical overview of the increasingly prominent…
specialty of global health. Originally developed from a course at Harvard Medical School, and now with contributions from nearly 100 world-renowned global health experts from across the globe, this textbook presents vital information required of students, trainees, and clinicians during their international experiences and training. Essential Clinical Global Health introduces readers to the up-to-date knowledge, skills, and approaches needed for productive and rewarding global health experiences. It provides essential clinical information on the diagnosis, management, and prevention of the leading causes of morbidity and mortality in low- and middle-income countries. The textbook also includes practical guidance on topics such as health systems, population-based approaches, cultural awareness and sensitivity, travel preparedness and safety, and career development in global health. With key learning objectives in each chapter, practical clinical advice, setting-appropriate guidelines, personal field experiences from student and clinician contributors, Essential Clinical Global Health is the first global health textbook with a clinical focus for healthcare students, trainees, and providers.A companion website at www.wileyessential.com/globalhealth features self-assessment questions and videos.Herz-Kreislauf (Springer-Lehrbuch)
Par Thomas F. Lüscher, Ulf Landmesser. 2024
Der Blick aufs GanzeEs ist immer wieder dasselbe: Wenn im klinischen Abschnitt endlich die spannenden Krankheitsbilder kommen, sind Anatomie und…
Physiologie längst vergessen. Mühsam muss man alles wiederholen, um zu verstehen, worum es bei der Erkrankung geht.Lernen Sie ein Organsystem doch einfach „am Stück“: von der Anatomie über die Physiologie bis zur Diagnostik und Therapie von Erkrankungen. Dieses Buch ist ideal für das Lernen im Modul, hier verstehen Sie das Organsystem im Zusammenhang. Die Erkrankungen des Herz-Kreislauf-Systems werden systematisch abgehandelt - endlich genügt ein einziges Buch, um den ganzen Themenblock durchzuarbeiten. Und dabei helfen Ihnen: Praktische Anleitungen für Diagnostik und TherapieZahlreiche diagnostische BilderNeueste Erkenntnisse und TherapieverfahrenMerksätze, Tabellen und Übersichten mit den wichtigsten FaktenWegen seiner Praxisnähe ist dieser Band sowohl für Medizinstudenten als auch für Ärzte in der kardiologischen Aus- und Weiterbildung bestens geeignet.Für die dritte Auflage wurde das Buch sorgfältig aktualisiert und um zwei neue Kapitel zur pulmonalen Hypertonie sowie Erkrankungen des venösen Systems ergänzt. So bleiben Sie auch mit der dritten Auflage am Puls der Zeit in der Kardiologie!Understanding Mental Health Apps: An Applied Psychosocial Perspective (Palgrave Studies in Cyberpsychology)
Par Lewis Goodings, Darren Ellis, Ian Tucker. 2024
This is the first book to look exclusively from at the use of MHapps from an applied psychosocial perspective. Much of…
the academic literature on MHapps in psychology focuses on the clinical efficacy of using apps (e.g., depression reduction as result of using a certain app) and will typically report on the use of randomised controlled trials (or a similar method) to illustrate the use of apps as a tool for improving a psychological condition. Therefore, the main benefit of this book is that it recognises the impact of apps from a social perspective and will aim to show how everyday forms of distress are embedded in the use of these apps and the broader set of relations that constitute people’s everyday lives. The content of this book will identify how an applied social perspective can offer insight into the power of apps to shape our sense of ourselves and of others. This book will be of use to educators and students in psychology, sociology, health studies, media studies andcultural studies.Surgery of Craniosynostosis and Related Midface Deformities: An Atlas and Step-by-Step Guide
Par Michael Rasse. 2024
This atlas offers a comprehensive overview of osteotomies performed on the calvaria and midface for both syndromic and non-syndromic craniosynostosis.It…
presents a systematic approach, beginning with calvarial osteotomies. The author introduces a general type of osteotomy that can be applied for total vault remodeling in cases of total synostosis. These osteotomies can also be modified and used in single or combined synostoses. To shape the calvaria, the book describes the use of metal plates as a scaphold. These plates can be prebent on 3-D models and used to fix the segments after osteotomies. Following that, resorbable osteosynthesis is performed, and the metal plates are subsequently removed. This unique approach, combined with standardized osteotomies, ensures highly predictable results that are not currently described in textbooks. The book includes clinical examples for each type of synostosis and various combinations, including two-stage procedures and combinations with distraction techniques. These examples provide surgeons with a solid foundation for addressing different cases. In the chapter on midface osteotomies, the book explains the access and technique for performing the LeFort-III osteotomy using cadaver and clinical figures. It covers all types of LeFort-I to III osteotomies and their combinations through clinical cases. The book illustrates the osteotomies, osteosynthesis, distraction techniques, and combinations using clinical examples. Additionally, the book demonstrates the method of computer planning, the fabrication of osteotomy guides, and the use of preformed plates to define the position of the segments.The book's primary objective is to serve as a surgical guide that transcends the boundaries of medical specialties. Given that this type of surgery is often performed by different specialists across institutions and countries, the book aims to facilitate cooperation and provide a practical application tool for surgeons beyond offering a clinical overview.The Balance Within: The Science Connecting Health and Emotions
Par Esther M. Sternberg. 2001
A thrilling scientific detective story, The Balance Within tells how researchers finally uncovered the elusive mind-body connection and what it…
means for our health. Since ancient times humans have felt intuitively that emotions and health are linked, and recently there has been much popular speculation about this notion. But until now, without compelling evidence, it has been impossible to say for sure that such a connection really exists and especially how it works. Now, that evidence has been discovered.In this beautifully written book, Dr. Esther Sternberg, whose discoveries were pivotal in helping to solve this mystery, provides first hand accounts of the breakthrough experiments that revealed the physical mechanisms - the nerves, cells, and hormones - used by the brain and immune system to communicate with each other. She describes just how stress can make us more susceptible to all types of illnesses, and how the immune system can alter our moods. Finally, she explains how our understanding of these connections in scientific terms is helping to answer such crucial questions as "Does stress make you sick?" "Is a positive outlook the key to better health?" and "How do our personal relationships, work, and other aspects of our lives affect our health?"A fascinating, elegantly written portrait of this rapidly emerging field with enormous potential for finding new ways to treat disease and cope with stress, The Balance Within is essential reading for anyone interested in making their body and mind whole again.One Thing at a Time: 100 Simple Ways to Live Clutter-Free Every Day
Par Cindy Glovinsky. 2004
Simple, effective ways to put things in their placeThose piles of papers, clothes, and other things you thought you'd successfully…
de-cluttered have returned, and this time they brought friends. What's the use of trying to fight the clutter? Is there a better way?This powerful and useful guide delivers solutions that work, no matter how overwhelmed you feel. The answer isn't an elaborate new system, or a solemn vow to start tomorrow. Instead, psychotherapist and organizer Cindy Glovinsky shares 100 simple strategies for tackling the problem the way it grows--one thing at a time. Here's a sampling of the tips explained in the book: *Declare a fix-it day*Purge deep storage areas first *Label it so you can read it*Get a great letter opener*Practice toy population planning *Leave it neater than you found itWritten in short takes and with a supportive tone, this is an essential, refreshing book that helps turn a hopeless struggle into a manageable part of life, one thing at a time.Knee Surgery: The Essential Step-by-Step Guide to Total Knee Recovery
Par Daniel Fulham O'Neill. 2009
In this age of same-day surgery and do-it-yourself health, Knee Surgery presents an easy-to-do, well-illustrated program of movement for knee…
rehabilitation - with a special focus on the mind/body connection - and describes the physical and mental rehabilitation process in complete detail, providing all the guidance you need to decrease pain and increase fitness after knee surgery. Millions of people have knee surgery each year, and in the years to come millions more will head to the O.R. Chances are, you or someone you know has had or will undergo knee surgery. Busy doctors, therapists, and athletic trainers have limited time to spend on quality physical and mental rehabilitation education, yet this is the key to full recovery.Written by renowned knee surgeon and Sport Psychologist Daniel F. O'Neill, M.D., Ed.D., this comprehensive and accessible guide presents what you'll want and need the most after knee surgery: a scientifically-based recovery program you can understand that will get you back to work and sports as quickly as possible.The Excruciating History of Dentistry: Toothsome Tales & Oral Oddities from Babylon to Braces
Par James Wynbrandt. 1998
For those on both sides of the dreaded dentist's chair, James Wynbrandt has written a witty, colorful, and richly informative…
history of the art and science of dentistry. To all of those dental patients whose whine rises in tandem with that of the drill, take note: You would do well to stifle your terror and instead offer thanks to Apollonia, the patron saint of toothache sufferers, that you face only fleeting discomfort rather than the disfiguring distress, or slow agonizing death oft meted out by dental-care providers of the past. The transition from yesterday's ignorance, misapprehension, and superstition to the enlightened and nerve-deadened protocols of today has been a long, slow, and very painful process.For example, did you know that: *Among the toothache remedies favored by Pierre Fauchard, the father of dentistry, was rinsing the mouth liberally with one's own urine.*George Washington never had wooden teeth. However, his chronic dental problems may have impacted the outcome of the American Revolution. *Soldiers in the Civil War needed at least two opposing front teeth to rip open powder envelopes. Some men called up for induction had their front teeth extracted to avoid service. *Teeth were harvested from as many as fifty thousand corpses after the Battle of Waterloo, a huge crop later used for dentures and transplants that became known as "Waterloo Teeth."The Matter of the Heart: A History of the Heart in Eleven Operations
Par Thomas Morris. 2017
An eye-opening and heroic story of pioneering heart surgeons, structured around eleven operations.For thousands of years the human heart remained…
the deepest of mysteries; both home to the soul and an organ too complex to touch, let alone operate on. Then, in the late nineteenth century, medics began going where no one had dared go before. The following decades saw the mysteries of the heart exposed, thanks to pioneering surgeons, brave patients and even sacrificial dogs. In eleven landmark operations, Thomas Morris tells us stories of triumph, reckless bravery, swaggering arrogance, jealousy and rivalry, and incredible ingenuity: the trail-blazing ‘blue baby’ procedure that transformed wheezing infants into pink, healthy children; the first human heart transplant, which made headline news around the globe. And yet the heart still feels sacred: just before the operation to fit one of the first artificial hearts, the patient’s wife asked the surgeon if he would still be able to love her.The Matter of the Heart gives us a view over the surgeon’s shoulder, showing us the heart’s inner workings and failings. It describes both a human story and a history of risk-taking that has ultimately saved millions of lives.The Fever: How Malaria Has Ruled Humankind for 500,000 Years
Par Sonia Shah. 2010
In recent years, malaria has emerged as a cause célèbre for voguish philanthropists. Bill Gates, Bono, and Laura Bush are…
only a few of the personalities who have lent their names—and opened their pocketbooks—in hopes of curing the disease. Still, in a time when every emergent disease inspires waves of panic, why aren't we doing more to eradicate one of our oldest foes? And how does a parasitic disease that we've known how to prevent for more than a century still infect 500 million people every year, killing nearly 1 million of them?In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.The book offers the update on several basic and clinical problems in neurosurgery compiled by internationally recognized experts. The main topics…
covered are cerebral tumors, epilepsy and vascular malformations, congenital and acquired spine anomalies.The first chapter is devoted to the genetic of the Moya-Moya disease, a cerebral vascular disease quite common in Asia that is not yet sufficiently known. The second chapter is devoted to the current application of VR/AR (virtual reality/augmented reality) to pediatric neurosurgery. The next four chapters discuss the management of spine diseases, respectively the tethered cord syndrome , the severe forms of spondylolisthesis, the role of perioperative checklists, and the long-term outcomes of myelomeningocele. Two chapters deal with the surgical aspects of the management of intraventricular tumors. Cerebral tumors, namely malignant gliomas and jugular foramen tumors are the subject of the remaining chapters.Approaching the issue of technical standards in the everyday clinical practice of neurosurgery, this book of great interest for neurosurgeons, neuroradiologists, vascular and plastic surgeons.Human-Centered Service Design for Healthcare Transformation: Development, Innovation, Change
Par Mario A. Pfannstiel. 2023
This book explores the use of human-centered service design. Through a variety of case studies and best practices, it highlights…
ways to systematically improve the provision of healthcare services to different target and age groups in order to understand customer expectations and needs. The book also offers new insights into the dyadic relationship between service provider and customer, each of which has their own set of goals, purposes, and benefits and must cope with a scarcity of resources and opportunities to optimize and design. Written by recognized experts, scholars, and practitioners, this book demonstrates how, where, and when to successfully apply human-centered service design at multiple levels, including corporate, departmental, and product/service. Value-added services are not only assessed in terms of their effectiveness, efficiency, and productivity, but also bearing in mind human emotions, interactions, and communication techniques as an important part of service provision. Accordingly, the book will appeal to scholars and practitioners in the hospital and healthcare sector, and to anyone interested in organizational development, service business model innovation, customer involvement and perceptions, and the service experience.A Psychological Approach to Diagnosis: Using the ICD-11 as a Framework
Par Geoffrey M. Reed, Pierre L.-J. Ritchie, Andreas Maercker, Tahilia J. Rebello. 2024
This groundbreaking volume, published by the American Psychological Association in partnership with the International Union of Psychological Science, provides a…
detailed guide to clinical diagnosis by psychologists and other health professionals based on the eleventh revision of the World Health Organization's International Classification of Diseases (ICD-11). The ICD-11 was adopted by the World Health Assembly in 2019 and came into effect as the global standard for health information and reporting in 2022. The ICD is the diagnostic system for mental disorders most widely used by mental health professionals around the world in their day-to-day clinical practice. This edited volume offers a step-by-step approach to diagnosis, giving mental health professionals around the world the tools they need to apply ICD-11 diagnostic requirements for mental, behavioral, and neurodevelopmental disorders as the basis for delivering high quality, evidence-informed care. A psychological approach to diagnosis is a conceptually driven, person-oriented, biopsychosociocultural formulation that integrates pertinent history, behavior, symptoms, phenomenology, and functioning. A psychological approach focuses on psychological mechanisms and principles as an aspect of diagnostic practice and case formulation, regardless of professional discipline. The chapters of this book cover the major groupings of mental disorder as well as related areas that are important parts of psychological practice, such as sexual dysfunctions, sleep-wake disorders, and relationship problems and maltreatment. The authors of this book are leading global experts in each area, many of whom were integrally involved in developing the respective sections of the ICD-11. Authors describe the overarching logic for the classificatory arrangement and the elements of a psychological approach to the set of disorders discussed in each chapter, including psychological models for conceptualizing their symptoms and recommendations for psychological assessment. The chapters also discuss presentations and symptom patterns for each major group of disorders, specifiers and subtypes, the threshold between normal variation and disorder, differential diagnoses, co-occurring disorders, developmental course, cultural and contextual considerations, and gender-related features. A Psychological Approach to Diagnosis is the first comprehensive training resource on WHO&’s ICD-11 classification of mental, behavioural and neurodevelopmental disorders. It provides practicing psychologists and other mental health professionals, primary care clinicians, educators, and trainees with essential tools for the competent practice of diagnosis using the ICD-11 as a framework.Psychological Approaches to the Treatment of Pediatric Obesity
Par Dr Crystal Stack Lim, Dr Elvin Thomaseo Burton. 2024
This book offers a comprehensive review of current research and theoretical approaches to pediatric obesity. Pediatric obesity is a significant…
public health concern that currently affects 1 in 5 children and adolescents. Prevention and treatment of this complex health condition requires a multifaceted approach that acknowledges the intersecting roles of gender, race and ethnicity, socioeconomic status, and other factors that play key roles in the onset and maintenance of pediatric obesity. Written for mental health clinicians, as well as medical practitioners such as physicians, nurses, dietitians, and exercise physiologists who care for children and adolescents, this helpful resource offers a comprehensive review of current research and theoretical approaches, as well as clear descriptions of effective strategies to prevent and treat pediatric obesity. Through a lens of diversity, equity, and inclusion, the authors incorporate cutting edge research and their extensive clinical experience and expertise as they review evidence-based treatments that can be incorporated into various settings, including primary care, mental health, and specialty medical care clinics as well as schools and community organizations. With a special focus on psychological factors, including mental health conditions that frequently co-occur with pediatric obesity, this book incorporates case examples, treatment guidelines, and reproducible handouts to make addressing pediatric obesity more accessible to clinicians and practitioners.Porth's Pathophysiology: Concepts of Altered Health States
Par Tommie L. Norris. 2025
Trusted for more than 40 years and updated to reflect today’s nursing challenges, Porth’s Pathophysiology: Concepts of Altered Health States,…
11th Edition, continues a legacy of excellence with a comprehensive, nursing-focused approach that instills a mastery of both the physical and psychological aspects of altered health. More approachable and inclusive than ever, this unique text clarifies complex ideas through diverse perspectives, the latest evidence-based information, and engaging in-text features and application exercises.Clinical Examples in Pediatric Rheumatology
Par Christian Huemer, Hermann Girschick. 2024
The book provides an introduction to the differential diagnosis and decision-making in pediatric rheumatological diseases through typical and real cases.…
One of the aspects in the discussion of various case scenarios is the avoidance of errors and error management. The casebook is useful for specialists and trainees in pediatrics, young doctors, and anyone on the path to specialization in pediatric rheumatology.The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.Restorative Techniques in Paediatric Dentistry: An Illustrated Guide to Conventional and Contemporary Approaches
Par M S Duggal, H Nazzal, A J Robertson. 2024
One of the first books on the market to illustrate the various clinical techniques for restoration, this revised and updated…
new edition offers new material on treatment planning, local analgesia, biomaterials, biological and contemporary approaches, and aesthetic crowns. The book addresses the specific needs of the paediatric patient and helps the clinician manage the restoration with those needs in mind. As a classic volume, it is essential for every dentist working with children and adolescent patients.Alternative Splicing and Cancer
Par Muzafar A. Macha, Ajaz A. Bhat, Surinder Kumar Batra. 2024
This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and…
diseases, particularly cancer. Diving deep into the complexities of gene expression and protein diversity, the book illuminates how abnormal splicing contributes to aggressive tumor formation, affecting cellular functions such as proliferation, survival, and immune evasion. With a focus on understanding molecular mechanisms, this book unravels potential diagnostic and prognostic targets, opening doors for enhanced anti-cancer treatment efficacy. An indispensable resource for anyone intrigued by the interplay between gene splicing and cancer biology, it paves the way towards innovative therapeutic strategies.