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Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis
Par Robert A. Copeland. 2023
ENZYMES A complete and approachable introduction to the study of enzymes, from theory to practice Enzymes catalyze the bulk of…
important biological processes, both metabolic and biochemical. They are specialized proteins whose function is determined by their structure, understanding which is therefore a key focus of biological, pharmacological, and agrarian research, among many others. A thorough knowledge of enzyme structure, pathways, and mechanisms is a fundamental building block of the life sciences and all others connected to them. Enzymes offers a detailed introduction to this critical subject. It analyzes enzyme proteins at the structural level and details the mechanisms by which they perform their catalyzing functions. The book’s in-depth engagement with primary literature and up-to-date research allows it to continuously deploy illustrative examples and connect readers with further research on key subjects. Fully updated after decades as the standard text, this book unlocks a thriving field of biological and biochemical research. Readers of the third edition of Enzymes will also find: Expanded chapters on steady-state and transient-state enzyme kinetics, structural components of enzymes, and more New chapters on enzyme regulation, enzyme-macromolecule interactions, enzyme evolution, and enzymes in human health Key Learning Points at the beginning of each chapter to assist students and instructors Enzymes promises to continue as the standard reference on this subject for practitioners of the life sciences and related fields in both academia and industry.The Disabled Body in Contemporary Art
Par Ann Millett-Gallant. 2024
The second edition offers an essential update to the foundational first edition, The Disabled Body in Contemporary Art. Featuring updated chapters…
and case studies, this second edition will not only expand on the first edition but will bring a new focus to contemporary disabled artists and their embodied, multimedia work.Essential Clinical Global Health (Essentials)
Par Brett D. Nelson. 2015
Essential Clinical Global Health is a brand-new, pioneering, and evidence-based textbook that provides a clinical overview of the increasingly prominent…
specialty of global health. Originally developed from a course at Harvard Medical School, and now with contributions from nearly 100 world-renowned global health experts from across the globe, this textbook presents vital information required of students, trainees, and clinicians during their international experiences and training. Essential Clinical Global Health introduces readers to the up-to-date knowledge, skills, and approaches needed for productive and rewarding global health experiences. It provides essential clinical information on the diagnosis, management, and prevention of the leading causes of morbidity and mortality in low- and middle-income countries. The textbook also includes practical guidance on topics such as health systems, population-based approaches, cultural awareness and sensitivity, travel preparedness and safety, and career development in global health. With key learning objectives in each chapter, practical clinical advice, setting-appropriate guidelines, personal field experiences from student and clinician contributors, Essential Clinical Global Health is the first global health textbook with a clinical focus for healthcare students, trainees, and providers.A companion website at www.wileyessential.com/globalhealth features self-assessment questions and videos.Herz-Kreislauf (Springer-Lehrbuch)
Par Thomas F. Lüscher, Ulf Landmesser. 2024
Der Blick aufs GanzeEs ist immer wieder dasselbe: Wenn im klinischen Abschnitt endlich die spannenden Krankheitsbilder kommen, sind Anatomie und…
Physiologie längst vergessen. Mühsam muss man alles wiederholen, um zu verstehen, worum es bei der Erkrankung geht.Lernen Sie ein Organsystem doch einfach „am Stück“: von der Anatomie über die Physiologie bis zur Diagnostik und Therapie von Erkrankungen. Dieses Buch ist ideal für das Lernen im Modul, hier verstehen Sie das Organsystem im Zusammenhang. Die Erkrankungen des Herz-Kreislauf-Systems werden systematisch abgehandelt - endlich genügt ein einziges Buch, um den ganzen Themenblock durchzuarbeiten. Und dabei helfen Ihnen: Praktische Anleitungen für Diagnostik und TherapieZahlreiche diagnostische BilderNeueste Erkenntnisse und TherapieverfahrenMerksätze, Tabellen und Übersichten mit den wichtigsten FaktenWegen seiner Praxisnähe ist dieser Band sowohl für Medizinstudenten als auch für Ärzte in der kardiologischen Aus- und Weiterbildung bestens geeignet.Für die dritte Auflage wurde das Buch sorgfältig aktualisiert und um zwei neue Kapitel zur pulmonalen Hypertonie sowie Erkrankungen des venösen Systems ergänzt. So bleiben Sie auch mit der dritten Auflage am Puls der Zeit in der Kardiologie!Understanding Mental Health Apps: An Applied Psychosocial Perspective (Palgrave Studies in Cyberpsychology)
Par Lewis Goodings, Darren Ellis, Ian Tucker. 2024
This is the first book to look exclusively from at the use of MHapps from an applied psychosocial perspective. Much of…
the academic literature on MHapps in psychology focuses on the clinical efficacy of using apps (e.g., depression reduction as result of using a certain app) and will typically report on the use of randomised controlled trials (or a similar method) to illustrate the use of apps as a tool for improving a psychological condition. Therefore, the main benefit of this book is that it recognises the impact of apps from a social perspective and will aim to show how everyday forms of distress are embedded in the use of these apps and the broader set of relations that constitute people’s everyday lives. The content of this book will identify how an applied social perspective can offer insight into the power of apps to shape our sense of ourselves and of others. This book will be of use to educators and students in psychology, sociology, health studies, media studies andcultural studies.Surgery of Craniosynostosis and Related Midface Deformities: An Atlas and Step-by-Step Guide
Par Michael Rasse. 2024
This atlas offers a comprehensive overview of osteotomies performed on the calvaria and midface for both syndromic and non-syndromic craniosynostosis.It…
presents a systematic approach, beginning with calvarial osteotomies. The author introduces a general type of osteotomy that can be applied for total vault remodeling in cases of total synostosis. These osteotomies can also be modified and used in single or combined synostoses. To shape the calvaria, the book describes the use of metal plates as a scaphold. These plates can be prebent on 3-D models and used to fix the segments after osteotomies. Following that, resorbable osteosynthesis is performed, and the metal plates are subsequently removed. This unique approach, combined with standardized osteotomies, ensures highly predictable results that are not currently described in textbooks. The book includes clinical examples for each type of synostosis and various combinations, including two-stage procedures and combinations with distraction techniques. These examples provide surgeons with a solid foundation for addressing different cases. In the chapter on midface osteotomies, the book explains the access and technique for performing the LeFort-III osteotomy using cadaver and clinical figures. It covers all types of LeFort-I to III osteotomies and their combinations through clinical cases. The book illustrates the osteotomies, osteosynthesis, distraction techniques, and combinations using clinical examples. Additionally, the book demonstrates the method of computer planning, the fabrication of osteotomy guides, and the use of preformed plates to define the position of the segments.The book's primary objective is to serve as a surgical guide that transcends the boundaries of medical specialties. Given that this type of surgery is often performed by different specialists across institutions and countries, the book aims to facilitate cooperation and provide a practical application tool for surgeons beyond offering a clinical overview.The Balance Within: The Science Connecting Health and Emotions
Par Esther M. Sternberg. 2001
A thrilling scientific detective story, The Balance Within tells how researchers finally uncovered the elusive mind-body connection and what it…
means for our health. Since ancient times humans have felt intuitively that emotions and health are linked, and recently there has been much popular speculation about this notion. But until now, without compelling evidence, it has been impossible to say for sure that such a connection really exists and especially how it works. Now, that evidence has been discovered.In this beautifully written book, Dr. Esther Sternberg, whose discoveries were pivotal in helping to solve this mystery, provides first hand accounts of the breakthrough experiments that revealed the physical mechanisms - the nerves, cells, and hormones - used by the brain and immune system to communicate with each other. She describes just how stress can make us more susceptible to all types of illnesses, and how the immune system can alter our moods. Finally, she explains how our understanding of these connections in scientific terms is helping to answer such crucial questions as "Does stress make you sick?" "Is a positive outlook the key to better health?" and "How do our personal relationships, work, and other aspects of our lives affect our health?"A fascinating, elegantly written portrait of this rapidly emerging field with enormous potential for finding new ways to treat disease and cope with stress, The Balance Within is essential reading for anyone interested in making their body and mind whole again.Admiral Nimitz: The Commander of the Pacific Ocean Theater
Par Brayton Harris. 2012
The biography of legendary admiral Chester W. Nimitz, master military strategist and visionary of submarine operations.Chester Nimitz was an admiral's…
Admiral, considered by many to be the greatest naval leader of the last century. After the attack on Pearl Harbor, Nimitz assembled the forces, selected the leaders, and - as commander of all U.S. and Allied air, land, and sea forces in the Pacific Ocean - led the charge one island at a time, one battle at a time, toward victory. A brilliant strategist, he astounded contemporaries by achieving military victories against fantastic odds, outpacing more flamboyant luminaries like General Douglas MacArthur and Admiral "Bull" Halsey. And he was there to accept, on behalf of the United States, the surrender of the Japanese aboard the battleship USS Missouri in August 1945. In this first biography in over three decades, Brayton Harris uses long-overlooked files and recently declassified documents to bring to life one of America's greatest wartime heroes.To Hell and Back: The Classic Memoir of World War II by America's Most Decorated Soldier
Par Audie Murphy. 1949
The classic bestselling war memoir by the most decorated American soldier in World War II. Originally published in 1949, To…
Hell and Back was a smash bestseller for fourteen weeks and later became a major motion picture starring Audie Murphy as himself. Many decades later, this classic wartime memoir is just as gripping as it was then. Desperate to see action but rejected by both the marines and paratroopers because he was too short, Murphy eventually found a home with the infantry. He fought through campaigns in Sicily, Italy, France, and Germany. Although still under twenty-one years old on V-E Day, he was credited with having killed, captured, or wounded 240 Germans. He emerged from the war as America's most decorated soldier, having received twenty-one medals, including our highest military decoration, the Congressional Medal of Honor. To Hell and Back is a powerfully real portrayal of American GI's at war.The Scariest Place in the World: A Marine Returns to North Korea
Par James Brady. 2005
A memoir from the New York Times bestselling author of Warning of War and Marines of Autumn, James Brady's The…
Scariest Place in the World. Half a century after he fought there as a young lieutenant of Marines, James Brady returns to the brooding Korean ridgelines and mountains to sound taps for a generation. It's been years since Brady first wrote of Korea in The Coldest War, drawing raves from Walter Cronkite and The New York Times, which called it "a superb personal memoir of the way it was." In the spring of 2003, Brady and Pulitzer Prize–winning combat photographer Eddie Adams flew in Black Hawk choppers and trekked the Demilitarized Zone where it meanders into North Korea, interviewing four-star generals and bunking in with tough U.S. recon troops, in Brady's words, "raw meat on the point of a sharpened stick." Brady recalls that first time on bloody Hill 749, the men who died there, what happened to the Marines who lived to make it home, and experiences yet again the emotional pull of a lifelong love affair with the Corps in which they all served. Brady summons up the past and illuminates the present, be it the Korea of "the forgotten war," the Yanks who fought there long ago, or today's soldiers standing wary sentinel over "the scariest place in the world." The result is uplifting, inspiring, often heartbreaking, and this Brady memoir proves as powerful as his first.Grant: A Biography (Great Generals Series)
Par John Mosier. 2006
Grant: A Biography tells of the extraordinary life and legacy of one of America's most ingenious military mindsA modest and…
unassuming man, Grant never lost a battle, leading the Union to victory over the Confederacy during the Civil War, ultimately becoming President of the reunited states. Grant revolutionized military warfare by creating new leadership tactics by integrating new technologies in classical military strategy. In this compelling biography, John Mosier reveals the man behind the military legend, showing how Grant's creativity and genius off the battlefield shaped him into one of our nation's greatest military leaders.Knee Surgery: The Essential Step-by-Step Guide to Total Knee Recovery
Par Daniel Fulham O'Neill. 2009
In this age of same-day surgery and do-it-yourself health, Knee Surgery presents an easy-to-do, well-illustrated program of movement for knee…
rehabilitation - with a special focus on the mind/body connection - and describes the physical and mental rehabilitation process in complete detail, providing all the guidance you need to decrease pain and increase fitness after knee surgery. Millions of people have knee surgery each year, and in the years to come millions more will head to the O.R. Chances are, you or someone you know has had or will undergo knee surgery. Busy doctors, therapists, and athletic trainers have limited time to spend on quality physical and mental rehabilitation education, yet this is the key to full recovery.Written by renowned knee surgeon and Sport Psychologist Daniel F. O'Neill, M.D., Ed.D., this comprehensive and accessible guide presents what you'll want and need the most after knee surgery: a scientifically-based recovery program you can understand that will get you back to work and sports as quickly as possible.The Excruciating History of Dentistry: Toothsome Tales & Oral Oddities from Babylon to Braces
Par James Wynbrandt. 1998
For those on both sides of the dreaded dentist's chair, James Wynbrandt has written a witty, colorful, and richly informative…
history of the art and science of dentistry. To all of those dental patients whose whine rises in tandem with that of the drill, take note: You would do well to stifle your terror and instead offer thanks to Apollonia, the patron saint of toothache sufferers, that you face only fleeting discomfort rather than the disfiguring distress, or slow agonizing death oft meted out by dental-care providers of the past. The transition from yesterday's ignorance, misapprehension, and superstition to the enlightened and nerve-deadened protocols of today has been a long, slow, and very painful process.For example, did you know that: *Among the toothache remedies favored by Pierre Fauchard, the father of dentistry, was rinsing the mouth liberally with one's own urine.*George Washington never had wooden teeth. However, his chronic dental problems may have impacted the outcome of the American Revolution. *Soldiers in the Civil War needed at least two opposing front teeth to rip open powder envelopes. Some men called up for induction had their front teeth extracted to avoid service. *Teeth were harvested from as many as fifty thousand corpses after the Battle of Waterloo, a huge crop later used for dentures and transplants that became known as "Waterloo Teeth."The Matter of the Heart: A History of the Heart in Eleven Operations
Par Thomas Morris. 2017
An eye-opening and heroic story of pioneering heart surgeons, structured around eleven operations.For thousands of years the human heart remained…
the deepest of mysteries; both home to the soul and an organ too complex to touch, let alone operate on. Then, in the late nineteenth century, medics began going where no one had dared go before. The following decades saw the mysteries of the heart exposed, thanks to pioneering surgeons, brave patients and even sacrificial dogs. In eleven landmark operations, Thomas Morris tells us stories of triumph, reckless bravery, swaggering arrogance, jealousy and rivalry, and incredible ingenuity: the trail-blazing ‘blue baby’ procedure that transformed wheezing infants into pink, healthy children; the first human heart transplant, which made headline news around the globe. And yet the heart still feels sacred: just before the operation to fit one of the first artificial hearts, the patient’s wife asked the surgeon if he would still be able to love her.The Matter of the Heart gives us a view over the surgeon’s shoulder, showing us the heart’s inner workings and failings. It describes both a human story and a history of risk-taking that has ultimately saved millions of lives.The Fever: How Malaria Has Ruled Humankind for 500,000 Years
Par Sonia Shah. 2010
In recent years, malaria has emerged as a cause célèbre for voguish philanthropists. Bill Gates, Bono, and Laura Bush are…
only a few of the personalities who have lent their names—and opened their pocketbooks—in hopes of curing the disease. Still, in a time when every emergent disease inspires waves of panic, why aren't we doing more to eradicate one of our oldest foes? And how does a parasitic disease that we've known how to prevent for more than a century still infect 500 million people every year, killing nearly 1 million of them?In The Fever, the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, The Fever captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.The book offers the update on several basic and clinical problems in neurosurgery compiled by internationally recognized experts. The main topics…
covered are cerebral tumors, epilepsy and vascular malformations, congenital and acquired spine anomalies.The first chapter is devoted to the genetic of the Moya-Moya disease, a cerebral vascular disease quite common in Asia that is not yet sufficiently known. The second chapter is devoted to the current application of VR/AR (virtual reality/augmented reality) to pediatric neurosurgery. The next four chapters discuss the management of spine diseases, respectively the tethered cord syndrome , the severe forms of spondylolisthesis, the role of perioperative checklists, and the long-term outcomes of myelomeningocele. Two chapters deal with the surgical aspects of the management of intraventricular tumors. Cerebral tumors, namely malignant gliomas and jugular foramen tumors are the subject of the remaining chapters.Approaching the issue of technical standards in the everyday clinical practice of neurosurgery, this book of great interest for neurosurgeons, neuroradiologists, vascular and plastic surgeons.Full Battle Rattle: My Story as the Longest-Serving Special Forces A-Team Soldier in American History
Par Changiz Lahidji, Ralph Pezzullo. 2018
Over 100 combat missions, 24 years as a Green Beret—Full Battle Rattle tells the legend of a soldier who served…
America in every war since Vietnam.Master Sergeant Changiz Lahidji served on Special Forces A teams longer than anyone in history, completing over a hundred combat missions in Afghanistan. Changiz is a Special Forces legend. He also happens to be the first Muslim Green Beret. Changiz served this country starting with Operation Eagle Claw in 1980, when he entered Tehran on a one-man mission to spy on Iranian soldiers guarding the US Embassy where 52 US diplomats were being held hostage. Three years later, he was in Beirut, Lebanon when a suicide car bomb exploded in front of the US Embassy killing 83 people. Weeks after that, he was shot by Hezbollah terrorists on a night mission. In Operation Iraqi Freedom, he led a convoy that was ambushed on its way to Fallujah. He was clearing houses in Mogadishu, Somalia on October, 1993 when a US Black Hawk helicopter was shot down 50 feet away from him in the incident that inspired Black Hawk Down. In 2002, he dressed as a farmer and snuck into Eastern Afghanistan and located Osama Bin Laden for the CIA. Along the way, Changiz earned numerous commendations, including the Special Forces Legion of Merit, Purple Hearts, and many others. Last year he was nominated for induction in Military Intelligence Hall of Fame and cited as “the finest noncommissioned officer to ever serve in Special Forces.” His story is an amazing tale of perseverance and courage, of combat and one man’s love of his adopted country.China's First Emperor and His Terracotta Warriors
Par Frances Wood. 2007
Unifier or destroyer, law-maker or tyrant? China's First Emperor (258-210 BC) has been the subject of debate for over 2,000…
years. He gave us the name by which China is known in the West and, by his unification or elimination of six states, he created imperial China. He stressed the rule of law but suppressed all opposition, burning books and burying scholars alive. His military achievements are reflected in the astonishing terracotta soldiers—a veritable buried army—that surround his tomb, and his Great Wall still fascinates the world.Despite his achievements, however, the First Emperor has been vilified since his death. China's First Emperor and His Terracotta Warriors describes his life and times and reflects the historical arguments over the real founder of China and one of the most important men in Chinese history.Giap: The General Who Defeated America in Vietnam
Par James A. Warren. 2013
An in-depth look at the strategy and tactics of the visionary commander who beat the United States in the Vietnam…
War.General Vo Nguyen Giap was the commander in chief of the communist armed forces during two of his country's most difficult conflicts—the first against Vietnam's colonial masters, the French, and the second against the most powerful nation on earth, the United States. After long and bloody conflicts, he defeated both Western powers and their Vietnamese allies, forever changing modern warfare. In Giap, military historian James A. Warren dives deep into the conflict to bring to life a revolutionary general and reveal the groundbreaking strategies that defeated world powers against incredible odds. Synthesizing ideas and tactics from an extraordinary range of sources, Giap was one of the first to realize that war is more than a series of battles between two armies and that victory can be won through the strength of a society's social fabric. As America's wars in the Middle East rage on, this is an important and timely look at a man who was a master at defeating his enemies even as they thought they were winning.Human-Centered Service Design for Healthcare Transformation: Development, Innovation, Change
Par Mario A. Pfannstiel. 2023
This book explores the use of human-centered service design. Through a variety of case studies and best practices, it highlights…
ways to systematically improve the provision of healthcare services to different target and age groups in order to understand customer expectations and needs. The book also offers new insights into the dyadic relationship between service provider and customer, each of which has their own set of goals, purposes, and benefits and must cope with a scarcity of resources and opportunities to optimize and design. Written by recognized experts, scholars, and practitioners, this book demonstrates how, where, and when to successfully apply human-centered service design at multiple levels, including corporate, departmental, and product/service. Value-added services are not only assessed in terms of their effectiveness, efficiency, and productivity, but also bearing in mind human emotions, interactions, and communication techniques as an important part of service provision. Accordingly, the book will appeal to scholars and practitioners in the hospital and healthcare sector, and to anyone interested in organizational development, service business model innovation, customer involvement and perceptions, and the service experience.