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Vanished Years
Par Rupert Everett. 2012
'[An] instant classic' IndependentRupert Everett's first memoir - Red Carpets and Other Banana Skins - was an international bestseller and…
an instant classic on publication in 2006. Reviewers compared him to Evelyn Waugh, David Niven, Noel Coward and Lord Byron. But Rupert Everett is - of course - one of a kind.Mischievous, touching and nothing less than brilliant, this new memoir is filled with stories, from childhood to the present. Astonishing encounters; tragedy and comedy; vivid portraits of friends and rivals; razor-sharp observations of the celebrity circus from LA to London and beyond... there is something extraordinary on every page. A pilgrimage to Lourdes with his father is both hilarious and moving. A misguided step into reality TV goes horribly wrong. From New York to Moscow to Berlin to Phnom Penh, Vanished Years takes the reader on a wild and wonderful new journey with a charming (and rather disreputable) companion.I Love My Computer Because My Friends Live in It: Stories from an Online Life
Par Jess Kimball Leslie. 2017
I Love My Computer Because My Friends Live in It is tech analyst Jess Kimball Leslie's hilarious, frank homage to…
the technology that contributed so significantly to the person she is today. From accounts of the lawless chat rooms of early AOL to the perpetual high school reunions that are modern-day Facebook and Instagram, her essays paint a clear picture: That all of us have a much more twisted, meaningful, emotional relationship with the online world than we realize or let on. Coming of age in suburban Connecticut in the late '80s and early '90s, Jess looked to the nascent Internet to find the tribes she couldn't find IRL: fellow Bette Midler fans; women who seemed impossibly sure of their sexuality; people who worked with computers every day as part of their actual jobs without being ridiculed as nerds. It's in large part because of her embrace of an online life that Jess is where she is now, happily married, with a wife, son, and dog, and making a living of analyzing Internet trends and forecasting the future of tech. She bets most people would credit technology for many of their successes, too, if they could only shed the notion that it's as a mind-numbing drug on which we're all overdosing.Go the Way Your Blood Beats: On Truth, Bisexuality and Desire
Par Michael Amherst. 2017
Using bisexuality as a frame, Go the Way Your Blood Beats questions the division of sexuality into straight and gay,…
in a timely exploration of the complex histories and psychologies of human desire. A challenge to the idea that sexuality can either ever be fully known or neatly categorised, it is a meditation on desire’s unknowability. Interwoven with anonymous addresses to past loves - the sex of whom remain obscure - the book demonstrates the universalism of desire, while at the same time the particularity of each individual act of desiring. Part essay, part memoir, part love letter, Go the Way Your Blood Beats asks us to see desire and sexuality as analogous with art - a mysterious, creative force, and one that remakes us in the act itself.Treatment of Thyroid Tumor
Par Hitoshi Noguchi, Takahiro Okamoto, Yasuhiro Ito, Hiroshi Takami, Akira Yoshida. 2012
Creating clinical guidelines is a modern trend. Published studies pertaining to a given theme are collected, their credibility evaluated, and…
then treatment options in the form of evidence-based guidelines are offered. There are a number of guidelines for the treatment of thyroid tumors that have established positions in clinical practice in North America and in Western European countries. In Japan, however, where radioisotope facilities are of limited availability, treatment plans for differentiated thyroid cancer differ considerably from those of America and Europe, and the associated clinical guidelines need modification before they can be adopted. In addition, although thyroid tumor is a common disease in endocrine practice, its management can differ even among specialists. Thus, a Japanese clinical guideline for the treatment of thyroid tumor was desired by many clinicians. As a combination of evidence-based and consensus-based guidelines for the treatment of thyroid tumor, this book offers alternatives to conventional approaches in the West. Ultimately, the authors hope the guideline will lead to the best possible treatment for patients all over the world in the not-distant future.My Miserable Lonely Lesbian Pregnancy
Par Andrea Askowitz. 2008
Everything You Need to Know to Manage Type 2 Diabetes: Simple Steps for Surviving and Thriving with the Low GI Plan
Par Kaye Foster-Powell, Jennie Brand-Miller, Stephen Colagiuri, Alan Barclay. 2007
A practical, easy-to-use guide to help you manage type 2 diabetes or prediabetes If you are one of the millions…
of people living with diabetes or prediabetes, you may feel like you're inundated with information on how to manage your condition. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it--and here, the world's foremost glycemic index experts share their wisdom. Rather than blind you with science or swamp you with facts, Everything You Need to Know to Manage Type 2 Diabetes sets out clearly and simply what you need to eat and do to help you: Reduce your risk of developing diabetes Improve your insulin sensitivity and your cardiovascular health Keep your blood glucose levels, blood pressure, and blood fats under control Reduce your body fat and maintain a healthy body With tips and strategies for working with your doctor, the most recent info on medications, and guidance on the best foods to eat (at home or at a restaurant), Everything You Need to Know to Manage Type 2 Diabetes offers uncomplicated, straightforward advice to help you survive--and thrive.Poster Girl
Par Beccy Cole. 2015
Beccy Cole's inspirational memoir from the heart of Australian country music.Beccy Cole has country music in her blood. Daughter of…
a country music star, Carole Sturtzel, she is one of the most popular country singer-songwriters in Australia today. This is the story of her life - in her own words.At fourteen, Beccy was performing in her mother's group, Wild Oats. By her late teens, Beccy had teamed up with the Dead Ringer Band - Kasey Chambers' family band - and had attracted the attention of the country music world by winning the Star Maker quest: the same award that started the careers of Keith Urban, Lee Kernaghan, James Blundell and Gina Jeffreys. It was just the first of many awards and accolades for this multitalented woman with a big heart.With refreshing candour, Beccy shares her story: leaving everything she knew to pursue her dream, making a name for herself with her own band; her marriage and motherhood; her subsequent divorce, becoming a single mother and maintaining the nurturing love of family. Performing for the Australian troops in Afghanistan. Coming out, and what it has meant for her and her fans. Taking control of her own life - and finding love.Heartfelt and honest, Poster Girl is the inspirational memoir of a strong woman who epitomises the authentic spirit of country music, and of Australia.Low GI Diet: Managing Type 2 Diabetes
Par Kaye Foster-Powell, Jennie Brand-Miller. 2014
The revised edition of the essential handbook on how to reduce the health risks posed by Type 2 Diabetes -…
from the team behind the internationally bestselling Low GI series. Are you living with type 2 diabetes or pre-diabetes and trying to manage your condition? In Australia and New Zealand alone diabetes and pre-diabetes affect 1 in 4 people. Every day nearly 300 people, including children, develop type 2 diabetes and for every person diagnosed with diabetes there's someone else with undiagnosed diabetes. The good news is that we now know a lot more about managing diabetes or reducing your risk of developing it. Low GI Diet: Managing Type 2 Diabetes cuts through the confusion of conflicting advice and sets out clearly and simply what you need to eat and do to help you: reduce your risk of developing diabetes; improve your cardiovascular health; keep your blood glucose levels, blood pressure and blood fats under control; and maintain a healthy body. This book is a practical guide to help you manage your diabetes or pre-diabetes with diet and lifestyle from the highly qualified, specialist team of authors led by world Low GI authority Professor Jennie Brand-Miller. It shows what you can do for yourself - and why. Best of all, this information is good advice for everyone in your family, not just you.Diabetes and Cardiovascular Disease
Par Francesco Paneni, Francesco Cosentino. 2015
This book provides a practical hands-on approach to the management of patients with diabetes and cardiovascular disease, with original and…
up-to-date coverage of a variety of aspects of emerging clinical importance. Practical advice is offered on diagnosis, risk stratification, management of cardiovascular risk factors and available drug therapies. Appropriate myocardial revascularization strategies are explained and the current state of knowledge is documented regarding target-led multifactorial treatment and the management of acute coronary syndromes, heart failure, and cerebrovascular disease. New algorithms for diagnosis and treatment are presented and to ensure ease of reference each chapter includes a box with practical recommendations as well as informative color illustrations and tables. The handbook will be of value for all cardiologists and diabetologists and will be especially helpful for young cardiologists, who are ever more frequently confronted by patients with diabetes and cardiovascular disease.Genetic Damage in Human Spermatozoa
Par Monica Muratori, Elisabetta Baldi. 2014
There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate…
during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.Thymic Development and Selection of T Lymphocytes
Par Thomas Boehm, Yousuke Takahama. 2014
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place.…
Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.Obesity and Breast Cancer
Par Kristy A. Brown, Evan R. Simpson. 2014
Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been…
shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters. Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer. Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast. This SpringerBrief will explore all of these issues in depth and the authors are in a unique position to write about this topic, having extensive experience in the field of aromatase research.The Cleveland Clinic Manual of Dynamic Endocrine Testing
Par Ahmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian. 2015
Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic…
has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.Stem Cell Therapy in Lysosomal Storage Diseases
Par Jaap Jan Boelens, Robert Wynn. 2013
Stem Cell therapy for lysosomal diseases (LSDs) is developing rapidly. This volume discusses the history, current practice and future perspectives…
of stem cells in inborn errors of metabolism (IEM) and provides an international perspective on progress, limitations, and future directions (e. g. gene therapy, iPS, ES) in the field. Beginning with an overview of these diseases, the book covers the breadth of this topic from treatment options, bone marrow transplantation, and alternative treatment options, through long-term outcomes and future perspectives.Therapeutic Perspectives in Type-1 Diabetes
Par Prachi Singh, Ganesh R Kokil, Karnaker R Tupally, Kingshuk Poddar, Aaron Tan, Venky Venkatesan, Harendra S. Parekh, Giorgia Pastorin. 2016
This book provides critical insights into and appraisals ofrecent breakthroughs in type 1 diabetes modulation, with a particular emphasison the…
potential impact of current prevention and treatment strategies. It alsodiscusses recent successes and failures in clinical trials. Presenting ancomprehensive overview of the disease, it is especially useful for newcomers inthe field. It also includes illustrations, which make it easy for the reader tograsp the basic concepts involved. Furthermore, the tables include concise andeasy-to-understand information on current clinical trials.Diabetes Management in Clinical Practice
Par Tahseen A. Chowdhury. 2014
At a time when clinicians are bombarded with masses of clinical information from numerous sources, and the wide variety of…
changes/advances in diabetes management, there is a need for a concise, easy-to-read book that provides an up-to-date review of the major advances in management of diabetes, with an evidence-based approach. This book is a collection of short chapters, each focused on a subject related to the management of diabetes and its complications. The chapters are written by acknowledged experts in the field, who are also clinicians dealing with diabetes on a day-to-day basis. The text is highly evidence based and well referenced with reviews of relevant trials. It includes the latest developments in diabetes management, prospects for future therapies and avenues of research, as well as therapies currently undergoing clinical trial. In order to facilitate ease of reading, it has a user-friendly appearance, with multiple headings, illustrations and summary boxes. The primary audience is clinical, including all healthcare professionals involved in the management of diabetes and its complications. This encompasses diabetologists and endocrinologists, family practitioners with an interest in diabetes, specialist nurses, dietitians and podiatrists.Glycemic Control in the Hospitalized Patient
Par Lillian F. Lien, Leonor Corsino, Mark N. Feinglos, Mary E. Cox. 2011
Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a unique, practical resource for health care providers dealing…
with hyperglycemia in the inpatient setting. Outlining a hands-on approach used by the Duke University Inpatient Diabetes Management team, the book discusses a wide range of scenarios that occur while treating patients with hyperglycemia, including challenging circumstances such as steroids and tube feeding regimens. Special emphasis is given to insulin therapy. The chapters are written by a group of health care providers with extensive, pioneering experience in hyperglycemia control in the inpatient setting at the Duke University Medical Center. The book includes the most up-to-date scientific evidence and information and is addressed to not only hospitalists and general internists but also endocrinology fellows, residents, nurse practitioners, nurses, and other primary care practitioners who treat patients in the inpatient setting. The focus is clearly on practical, patient-care topics. Glycemic Control in the Hospitalized Patient: A Comprehensive Clinical Guide is a first-of-its kind, comprehensive guide to state-of-the-art inpatient glycemic management.Hormones, Intrauterine Health and Programming
Par Jonathan R Seckl, Yves Christen. 2014
The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming.…
The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis is made on the emerging science of epigenetics as a potential explanation for how environmental events that occur during brief windows of development may exert effects that impact upon somatic cells through many rounds of mitosis for much of the life span of the subsequent organism.Managing Diabetic Nephropathies in Clinical Practice
Par George L. L. Bakris, Allison Hahr, Romesh Khardori, Daisuke Koya, Mark Molitch, Friedrich C. C. Prischl, Guntram Schernthaner, Bijin Thajudeen. 2017
An overview of the diagnosis, treatment, and long-term management of diabetic-related kidney disease in clinical practice. Includes an evidence-based discussion…
of currently available and experimental drug therapies currently in development, guided by international consensus guidelines. Ideal for physicians, medical trainees, nurses and other medical professional that regularly screen and treat patients with all types of diabetes.The Complete Diabetes Organizer
Par Leslie Josel, Susan Weiner. 2013
Is your lack of organization impacting your ability to effectively manage your diabetes? Do you run out of supplies and…
forget endocrinologist appointments? Do you find snacks in your pantry that expired sometime before the insulin pump was invented? Do you struggle to keep track of health-care invoices and payments? Do you succeed at keeping an active health journal for a week or two and then neglect it for a year or two?It sounds like you could use The Complete Diabetes Organizer!Within the pages of this book, diabetes educator Susan Weiner and organizing guru Leslie Josel provide you with dependable strategies and ideas designed to help streamline your diabetes care and simplify your life. From her distinguished career and experience in the fields of diabetes and dietetics, Susan Weiner brings helpful tips and tricks that are guaranteed to ease daily mechanics, promote improved nutrition, and relieve stress caused by disorder and confusion. Certified professional organizer and ADHD Specialist Leslie Josel applies her expertise to the topic of diabetes, with simple, surefire techniques that will allow you to disentangle yourself from the clutches of chronic disorganization.The Complete Diabetes Organizer is your guidebook to maintaining your diabetes with less effort and more confidence, allowing you to focus on enjoying a healthier, stress-free life.