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This book discusses the potential application of self-nanoemulsifying drug delivery systems (SNEDDS) in different inflammatory diseases. It introduces the fundamental…
principles of SNEDDS, their formulation components, and characterization techniques, providing insights into their mechanisms of drug delivery and formulation optimization. The book also explores the potential of various combination therapies with SNEDDS, highlighting strategies, synergistic effects, and challenges. Furthermore, the chapters in the book highlight the applications of SNEDDS in specific inflammatory diseases, including diabetes, brain diseases, colorectal diseases, cardiovascular diseases, lung diseases, and cancer. Towards the end, the book evaluates the potential toxic effects of SNEDDS components and addresses safety considerations, regulatory aspects, patents, and clinical trials pertaining to SNEDDS. This book is intended for researchers, pharmacologists, pharmaceutical scientists, and clinicians involved in drug delivery and nanomedicine.
This book presents an introduction to the field of information technology (IT) suitable for any student of an IT-related field…
or IT professional. Coverage includes such IT topics as IT careers, computer hardware (central processing unit [CPU], memory, input/output [I/O], storage, computer network devices), software (operating systems, applications software, programming), network protocols, binary numbers and Boolean logic, information security and a look at both Windows and Linux. Many of these topics are covered in depth with numerous examples presented throughout the text.New to this edition are chapters on new trends in technology, including block chain, quantum computing and artificial intelligence, and the negative impact of computer usage, including how computer usage impacts our health, e-waste and concerns over Internet usage. The material on Windows and Linux has been updated and refined. Some content has been removed from the book to be made available as online supplemental readings.Ancillary content for students and readers of the book is available from the textbook’s companion website, including a lab manual, lecture notes, supplemental readings and chapter reviews. For instructors, there is an instructor’s manual including answers to the chapter review questions and a testbank.
This book is an invaluable quick reference resource for clinicians and a useful study guide for veterinary students and residents.This…
practical and beautifully illustrated book takes you on a walk through avian medicine, beginning with the basics, such as common species, husbandry, nutrition, and grooming, before moving on to the more clinical-focused material, such as how to perform a physical examination, collect samples and interpret diagnostic tests, take good quality radiographs and then interpret them, and how to support a sick bird while in hospital.It then moves into the disorders affecting the different organs and body systems. Each chapter begins with a description of clinical anatomy and physiology before going on to explore the disorders associated with the effects of disease or trauma. The book also addresses behavioural problems, incubation of eggs, paediatrics, anaesthesia, and surgery.For this edition, Bob Doneley is joined by avian, zoo/wildlife and exotic pet veterinarian Shangzhe Xie. Together they have thoroughly updated the book by incorporating the latest research and covering a larger range of avian species. Building on the practical aspects that make this book stand out from other resources, they have added step-by-step pictorial guides to common procedures and surgeries, as well as videos for longer, more complicated ones. Avian Medicine and Surgery in Practice will therefore allow the practitioner to immediately help the patient at hand, whether to prescribe a medication or perform a life-saving surgery.
Biomedical Materials and Biofabrication for Regenerative Medicine addresses the existing and future trends of tissue engineering approaches for regenerating various…
organs/tissues. This book brings together leading experts to explore the latest innovations and applications in this dynamic field. From biomaterials design to scaffold development to 3D bioprinting, each chapter delves into cutting-edge research and practical insights shaping the future of healthcare. This book also provides a comprehensive overview of the advanced technologies for tissue engineering approaches for both in vitro and in vivo functions, which includes possibilities, challenges, and future aspects of biofabrication. The book will serve as a valuable resource to bridge the gap between material science and clinical applications, offering insights for researchers, clinicians, and students interested in the future of regenerative therapies, and inspiring new ideas and collaboration in the quest to heal and regenerate human tissues.
Both food security and agriculture contribute to, and are affected by, global climate change. The Intergovernmental Panel on Climate Change…
reports that food production systems account for up to 37% of global greenhouse gas emissions. At the same time, these systems are increasingly vulnerable to climate change, with extreme weather events such as rising temperatures, flooding, drought, secondary salinity, and land degradation threatening food security in South Asia. Additionally, the spread of weeds, pests, and diseases due to shifting climates exacerbates these challenges. The strain on agriculture and food security from accelerated climate change is further worsening by rapid population growth. Globally, more than 820 million people suffer from hunger, and by 2050, food production will need to double to meet global demands. This intensification of farming, combined with climate change, will lead to greater reliance on reactive chemicals, water, and energy inputs—potentially damaging agroecosystem services and becoming increasingly difficult to manage. South Asia, with its high population growth, is particularly vulnerable to climate impacts such as flooding, salinity, droughts, and solar dimming. Rising sea levels and coastal erosion could result in the loss of 17% of land surface and 30% of food production by 2050.Agriculture and food systems must undergo innovative transformations to address these challenges. A comprehensive Climate Change Adaption Framework is essential for fostering a supportive policy environment, sharing information on climate impacts, and adapting climate-smart agriculture to enhance food security in South Asia. This book, based on the outcomes of the 2022 International Conference on Climate Change and Food security in South Asia, held in Dhaka, Bangladesh, explores key challenges and innovative solutions for mitigating and adapting to the impact of climate change on food security.
This book combines Construction 6.0 with AEC principles for designing sustainable, health-focused Martian habitats. It unveils innovative architectural designs ideal…
for Mars, utilizing 3D printing, autonomous robotics, and regolith, alongside renewable energy and life support systems. With an emphasis on well-being, it integrates biophilic design and digital technologies to enhance operational efficiency. Exploring various habitat models, it advocates a multidisciplinary approach to extraterrestrial colonization that balances technological advancement with environmental and ethical stewardship, aiming to make human life on Mars a healthy and sustainable reality.
'You deserve to exist as your biggest, unapologetic and most whole self. You always have done.'Bestselling author Megan Jayne Crabbe…
lays bare all the ways we shrink ourselves in today's world, and how to break free.From body ideals to bad break ups, sexual shame to toxic productivity, Megan interrogates how cultural and internal narratives diminish us and explores what we can do to ditch social pressures and live life as our fullest and boldest selves.Candid, empowering and insightful, We Don't Make Ourselves Smaller Here is a powerful rallying cry for embracing authenticity in all areas of our lives. It is an invitation to revisit the places where parts of us were lost, taken or given away, and to reclaim them.
'That thing in Tiltspire, it keeps Cahan like a trophy. It says to us, here is your strongest and I…
have killed him.'Cahan Du Nahare is lost, taken by a dark god whose tendrils reach throughout the world, intent on its destruction. Those who followed Cahan are spread across the land, desperate and lost now fate has turned against them. The Reborn warriors are toys for the enemy, the warrior Dassit, forestal Ania and monk Ont are drawn to the dangerous north but do not know why. Udinny is forced into the company of a woman who desires nothing more than her death and the Rai, Sorha, leads a dwindling band on a mission even she believes is doomed to failure. Only the trion Venn remains hopeful, slowly growing in power and trusting in the path of their god.But maybe all is not lost, the great Wyrdwoods of Crua may be ancient and slow to act, but something in them is waking.Wyrdwood is coming.
**From the bestselling author of THE WALKER'S GUIDE TO OUTDOOR CLUES AND SIGNS and HOW TO READ WATER, The Sunday…
Times Book Of The Year**Tristan Gooley, author of THE NATURAL NAVIGATOR demonstrates how it is possible to connect profoundly with the lands we travel through, even from the comfort of your living room. In THE NATURAL EXPLORER he combines the work of the some of the most insightful travellers of the past two thousand years with his own experience.The most rewarding travel experiences do not depend on our destination or the length of our journey, but on our levels of awareness. A short walk can compare with an epic journey, when we take the time to focus on the things that dramatically enrich each journey.Exploration is no longer about hardship, long distances, or even venturing beyond the borders of your own home. It is about celebrating the sense of connection and discovery that is possible in all our travels.
'We have a case to solve, remember, Mr. Writer?'Zofia's son, Janek, has vanished without a trace. Leaving behind her native…
Warsaw, she arrives in London, determined to uncover the truth - and she's certain that a celebrated writer called Steve holds the key to Janek's disappearance.To fund her DIY investigation, Zofia takes on a string of cleaning jobs - a professional trajectory she finds very much beneath her. Armed with little more than her stubborn resolve and a second-hand detective manual, Zofia gathers evidence. After all, mother knows best - something she proves when she makes a shocking discovery: Steve's now dating Janek's ex-boyfriend. After some further digging it transpires that a former lover is not the only thing Steve has stolen from Janek...Despite their mutual animosity, Zofia and Steve team up to get to the bottom of this tangled web of lies. Facing an unsolved murder, a stolen manuscript and a missing son, this unlikely duo must confront the secrets they've been hiding - not just from each other but from themselves.With biting humour and a detective you've definitely never met before who breaks *every* rule in the book, Zofia Nowak's Book of Superior Detecting will keep you guessing - and laughing - until the very last page. Perfect for fans of Jonas Jonasson, Elizabeth is Missing and Eleanor Oliphant is Completely Fine.'If you're looking for irresistible prose, it's here in this book. The protagonists' voices criss-cross in a near impossible harmony of heart, guts, shrewdness and nerve... I'm in awe' Helen Oyeyemi
What does it mean to live in a world that punishes distraction, but profits from our attention?Why do so many…
ADHD individuals not feel at home at school or in the workplace? What does it really feel like to grow up, learn, work and exist in a world that wasn't built for your brain?Why are so many of us struggling with shame, burnout and - statistically speaking - a suspicious number of parking tickets?Attention Seeker is a groundbreaking, unfiltered exploration of ADHD - how it shapes lives across race, gender, and class, and why so many people are left undiagnosed and misunderstood.Drawing on research, lived experience and the realities of navigating ADHD in the UK today, Medland cuts through the myths and misinformation to uncover the truth. From education to employment, addiction to the criminal justice system, Attention Seeker reveals how ADHD intersects with power, privilege and oppression - and what needs to change.Ending with a bold anti-capitalist manifesto, Medland challenges everything we think we know about ADHD. The book asks: in a society obsessed with productivity and perfection, what can everyone learn from those who think differently?Attention Seeker is the first book of its kind. Equal parts eye-opening, urgent and authoritative, this is a call to rethink ADHD, not just as an individual diagnosis, but as a political issue.
After achieving her lifelong dream of solving a murder, Beatrice Steele feels like everything is finally falling into place. Accompanied…
by her ever-trusty chaperone, Miss Bolton, she's traded her small town for London and opened a new office with prickly, annoyingly logical Inspector Drake to solve the city's brutally thrilling crimes.However, nothing is turning out how Beatrice imagined it would. Famed gentleman inspector Sir Huxley is considered the real investigator in London, so the only cases left for Beatrice and Drake are lost pets and spectacles. Not that Beatrice has much time for crime-solving, anyways, as her mother still expects her to find an eligible husband to protect their family from destitution. That is until a string of murders thrusts Beatrice and Drake into the center of a scandal that spreads fear and chaos throughout the city. As they follow the trail through bewildering ballrooms, secretive shops, and odd operas, Beatrice must break the case--before it's too late.
A hidden power. A sinister force. A mystery she can't ignore.In a near-future London where technology affects everything from our…
bodies to our politics, journalist Pels Badmus wants to make a real difference. She's desperate to solve a spate of disappearances of young Black kids-including her friend's brother. But her boss doesn't want to hear it. Instead, he assigns her to cover the "unreasonable" protests thousands of miles away in Benin, against culturally oblivious tourists travelling to partake in sacred Spirit Vine rituals. Pels soon finds herself in West Africa, ignoring her boss's motives in assigning her to this piece and hoping to use it as leverage later. She's also trying to ignore the strange, ethereal dreams she's been having...However, when Pels takes the Spirit Vine herself, she experiences something mind-boggling. Something that points to an unfulfilled destiny that could change the course of her life. But first she must return home and confront an otherworldly conspiracy related to the missing children. Because she may just be the only one able to stop it.A bold imagining of our future through the lens of ancient spirituality, Awakened is a page-turning fable about a Black woman coming into her power, perfect for fans of N.K Jemisin and Netflix's Supacell.
Are you keen to banish burnout for good? Burnout-Free Working is written by Dr Richard Duggins - a leading expert…
and trainer on preventing burnout in high stress jobs, also known as 'The Doctor's Doctor'. In this book he reveals the secrets of his trade for the first time. With a wealth of proven tools for burnout-free working, Dr Duggins covers all you need to know, including:- Spotting early signs of burnout - Steering clear of 'the burnout cliff'- Tackling 'Keep calm and carry on' culture- Detoxifying workplace environments- Dealing with trauma at work- Moving from Stress to Decompress- Strategies to support colleagues Dr Duggins breaks down common burnout myths (it's really not about building resilience!) and encourages us all to shift our thinking away from burnout recovery, to instead living and working in a way that avoids burnout before you even get close.
'Terrific and passionate writing about a philosopher whose heroism is unquestionable . . . and as lively and learned an…
introduction to classical Athens as you could want' - Daily TelegraphIn The Hemlock Cup, award-winning historian Bettany Hughes brings to vivid life one of the most influential thinkers the world has ever known: Socrates of Athens. A maverick philosopher who philosophised in squares and public arenas rather than the courts of kings, Socrates left his indelible mark on the entirety of Western civilisation - yet the life of the man himself is shrouded in mystery.What would life have been like in the Athens of Socrates's youth? How did the Socratic method come to dominate the way we think and learn? And what can Socrates teach us about how we should live? Drawing on fresh evidence and the latest archaeological discoveries, Bettany Hughes finally gives Socrates the biography he deserves - and shows just how relevant he remains to this day.
Income inequality in America has been on the rise for decades, but policy and legal thought has yet to catch…
up. Both parties in the United States have been hesitant to intervene in the market to address this problem, while the income tax system has been touted as a better and more efficient way to tackle income inequality. However, the tax system itself has failed to keep pace with the widening gaps in income. Ending Income Inequality challenges arguments made by legal scholars in the field of law and economics, who have supported the tax system over redistributive legal rules. By examining specific areas of the law such as minimum wage, collective bargaining, antitrust law, intellectual property, and housing regulation, the book argues that using legal rules, in addition to income taxes, is a promising path to reverse rising inequality.
Immunohistochemistry and ancillary studies play a crucial role in diagnostic pathology. Yet, few books cover their practicality in diagnostic dermatopathology.…
This book provides a practical guide to the application of rapid and cost-effective immunohistochemistry, as well as ancillary studies including immunofluorescence and molecular studies. With a focus on practicality and bridging knowledge gaps, the book covers helpful diagnostic stains and pertinent ancillary studies, organized by lines of differentiation. Each chapter includes a synopsis of antibodies, immunohistochemical panels, summary tables outlining staining patterns, and case studies. Now in its second edition, this book covers entities based on lineage, including epithelial, adnexal, melanocytic, lymphoid, and soft tissue, and discusses the role of molecular studies in the diagnosis of cutaneous neoplasms and soft tissue lesions. This comprehensive volume is an essential resource for pathologists, dermatopathologists, and residents in pathology and dermatology.
The approach of Latin American countries to preferential trade agreements (PTAs) is a fascinating topic. There is a rich history…
of policymakers using PTAs to pursue different economic and political models of integration. What really stands out is the diversity of approaches and attitudes to the use of PTAs. While some countries have been rule-makers and have made innovative attempts to introduce new issues, others have been reluctant to use PTAs. In response to the growing interest in and politicisation of PTAs in the wider public – including renewed consideration of 'with whom to trade' – this book brings together scholars from inside and outside Latin America to address the past, present, and future challenges associated with PTAs. The contributions, from a variety of disciplinary backgrounds, offer new insights into issues related to the design, diffusion, and impact of PTAs. This title is also available as open access on Cambridge Core.
Drawing from extensive developmental research, this book highlights the significance of meaning in shaping individual worldviews within relationships, from infancy…
onwards. By focusing on behavior and experience, it reshapes our understanding of pertinent psychological phenomena, tracing the emergence of self, self-regulation, causality comprehension, peer relationships, adolescent experiences, and lifelong adaptation. Using developmental psychology and compelling clinical cases, the authors emphasize the central role of 'meaning' as a unifying theme, addressing diverse topics such as resilience, intergenerational behavior patterns, trauma impacts, and existential meaning. Ideal for students and professionals in psychology, counselling, and social work, as well as researchers and clinicians in related fields, this book integrates existing theories and empirical evidence to illuminate various aspects of human development and adaptation.
In 1893 Clara Lindow sang the ballad Dreamtide to her own guitar accompaniment in the Cumbrian hamlet of Lowick. A…
writer for the local newspaper not only admired her 'marked skill and ability' but also considered the concert to be a sign of 'the onward march of light and learning in our time'. Amateurs like Miss Lindow were at the heart of a Victorian revival of guitar playing, especially for accompanying the voice, which has never been fully acknowledged and has often been denied. This book is a ground-breaking history of the guitar and its players during the era when the Victorians were making modern Britain. The abundant newspaper record of the period, much of which is now searchable with digital tools, reveals an increasingly buoyant guitar scene from the 1860s onwards. No part of Victorian life, from palace to pavement, remained untouched by the revival.