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Articles 441 à 460 sur 636
Par Christos P. Panteliadis, Ramsis Benjamin, Christian Hagel. 2022
This book provides extensive data on the more common and many of the more rare congenital and hereditary syndromes that…
manifest in the nervous system and skin. Though often complex and multi-systemic, these disorders can frequently be diagnosed using a combination of simple visual inspection and sound clinical expertise. Drawing on fully referenced information from thousands of articles, the international editorial team has prepared a comprehensive overview that includes historical perspectives, clinical features, the pathogenesis, and diagnostic and therapeutic strategies. In addition, it addresses the biochemical, molecular, and genetic basis of the disorders. The book is divided into four main sections. Starting with general aspects of aetiology, diagnostics and therapy, the first part then covers the genetics, neuro-imaging, neuropathology, ocular manifestations and surgical management. The second part discusses developmental malformations, such as Sturge-Weber syndrome, Ataxia-Telangiectasia, Hypomelanosis of Ito and other rare syndromes, including haemangiomas. The focus of the third part is on tumour suppressor/DNA repair disorders, the most common of which is Neurofibromatosis 1. It also describes Neurofibromatosis 2, Schwannomatosis, Tuberous sclerosis, von Hippel-Lindau disease, Naevoid basal cell carcinoma and others. The book’s fourth and final section covers defects in enzymes and structural proteins, which manifest as Cerebrotendinous xanthromatosis, Ehlers-Danlos syndrome, Menkes syndrome, Refsum disease.Par Xinghuai Sun, Yi Dai. 2019
This book provides comprehensive information on current medications for glaucoma. From anatomy and physiology of glaucoma related ocular structure to…
the current mechanism theories and evaluation techniques of glaucoma, our understanding of glaucoma has been considerably improved in the last three decades. A large number of medications have been developed for the treatment of glaucoma, whose pharmacological information and data on efficacy and safety will be introduced in detail in this book. Practical guidelines for different type of glaucoma and specific patients, and pharmaceutical agents combined usage are concise and credible. The other chapters on patient managements and updates on glaucoma guidelines add useful and practical information to the book. New experimental and clinical investigations are promising and may develop new therapeutic targets for treatment of glaucoma in future.The primary target audience for this book is practicing ophthalmologists and ophthalmologists in training. Other healthcare professionals who need information about medical treatment for glaucoma may also find this book valuable. We will provide both evidence-based information and clinical experience on antiglaucoma medications, and guide the clinician on how to use them for the patient’s maximal benefit.Par H. V. Nema, Nitin Nema. 2022
The book focuses on describing the importance of genetics in eye diseases in a comprehensive and concise manner. Mutations in different…
set of genes have been detected and incriminated in complex mechanisms of causing leading eye diseases such as cataract and glaucoma. This book written by well-established ophthalmologists and geneticists presents a complicated subject in simple and easy to understand manner. Chapters cover the concept of gene therapy which is an emerging subject with high potential. The book includes a separate chapter on genetic counseling, which has become an integral component of ophthalmology. The book will assist the practicing ophthalmologists in early diagnosis of genetic eye diseases as well as help the geneticists in understaning the basic concepts. It will also be useful for students who are preparing for MD, MS, DNB and FRCS examinations.Par Uday B. Kompella, Seshadri Neervannan. 2021
This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on…
anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances.Par Hyeong-Gon Yu. 2022
This book presents the latest knowledge and expert guidance on all aspects of inherited retinal diseases, including molecular genetics, diagnosis,…
clinical features, general principles of treatment, novel treatment methods, and genetic counseling. Recent years have witnessed great advances in understanding of the genetic and cytological background of these diseases. Genetic analysis methods such as next generation sequencing have remarkably reduced the cost and time required for massive analysis of patients’ samples. Studies on gene therapy and stem cell therapy have been successfully carried out in animal models, and gene therapy is now available for Leber congenital amaurosis caused by RPE65 mutations. Against this background, Inherited Retinal Disease will be an invaluable up-to-date resource for ophthalmologists, medical students, and researchers in ocular inflammation. In addition to supplying essential information on each individual disorder, it features many interesting cases contributed by global leaders in the field as well as clinical photographs obtained with newer imaging techniques and numerous images of rare but clinically important diseases.Par Golshan Latifi, Scott Hau. 2022
In Vivo Confocal Microscopy in Eye Disease is a comprehensive new text that covers the latest advances in the field of in…
vivo confocal imaging. It presents a detailed overview of the basic anatomy of the different part of the cornea, conjunctiva and adnexal structures. It discusses the use of in vivo confocal microscopy in a range of clinical applications including the diagnosis of infective keratitis, corneal dystrophies, cornea nerves, conjunctival diseases and their differentiating features. Numerous confocal images, clinical pictures, other paraclinical images and histopathology slides of different ocular pathologies are examined and presented throughout the text. This book systematically reviews the use of confocal imaging in basic science of ocular tissues to the diagnosis of eye disease assembled in a single volume. It provides an up to date resource with an in depth review of scientific literature relating to both the clinical and research application of in vivo confocal microscopy in eye disease. The book ends with a discussion on non-ocular application of in vivo confocal microscopy and future developments including other emerging imaging technologies. This text will provide an invaluable resource for those who are interested in ocular imaging and it represents a timely resource for all practicing and trainee ophthalmologistsPar Hans Bebie, Josef Flammer, Maneli Mozaffarieh. 2012
Basic Sciences in Ophthalmology aims to link clinical ophthalmology directly to its basic science roots This first volume describes…
the physics and chemistry required for a sound understanding of modern ophthalmology The book opens with an extensive discussion of the interaction of light with matter and the way in which light is used in ophthalmic examinations and treatments After describing traditional methods of imaging particular emphasis is placed on modern instrumentation such as OCT The interaction between light and tissues in different types of laser treatment is also addressed The chemistry section focuses on compounds particularly relevant to the eye such as oxygen and water The origin and consequences of oxidative stress are reviewed and the physical behavior of chemical compounds in the eye is explained Understanding is facilitated through the use of many examples taken from the field of ophthalmology The text is complemented by about 450 figuresPar Ulrich Spandau, Gabor B. Scharioth. 2022
Every cataract surgeon is afraid of complications, but while complications cannot be entirely avoided, it is possible to learn to…
master them. This practical book clearly explains how to manage the various complications that may arise during cataract surgery, from a subluxated intraocular lens to a dropped nucleus. It provides the surgeon with clear instructions on how best to proceed in the manner of a cookbook, by first describing the ingredients (equipment), preparation (planning) and then providing step-by-step descriptions of technique with the aid of numerous helpful color illustrations.Complications During and After Cataract Surgery: From Phacoemulsification over Secondary IOL Implantation to Dropped Nucleus, 2nd Edition includes fully revised chapters outlining technical developments and new chapters on trocar surgery from pars plana and surgical management of a dropped nucleus with a cataract machine. Readers wishing to learn techniques for managing a full range of potential complications will find this book to be an essential resource.Par Nishi Gupta, Santhosh G. Honavar. 2022
This book is the most comprehensive (and possibly the first) manual on ‘Rhino-Orbito-Cerebral Mucormycosis (ROCM) that covers mucormycosis of the…
nose extending to sinuses, orbit, and brain, all in. This volume covers the surge of cases during the COVID-19 pandemic, early identification and causative factors, microbiology, pathology and radiology, and the clinical presentation. Notes on surgical approaches, extent, and techniques of debridement, number of sittings, antifungal therapy, complications, and their management equip readers to manage these cases confidently. Detailed descriptions of ROCM surgery accompanied by nearly 500 photographs and anatomical drawings help support diagnostic and surgical decision-making. Also included is information on various specifications of MRI that help in achieving a perfect surgical clearance. The book includes chapters on debates on salvaging the orbit in ROCM, various situations, their management, the extent of resection, antifungal dosage and duration, prognostication of the patient, and postoperative care. The book assists surgeons in gaining the skills to perform endoscopic clearance of difficult areas like pterygoplataine fossa, infratemporal fossa, pterygoid plates, and the lacrimal drainage system, which offers significant advantages in terms of avoiding postoperative morbidity as compared to an external route. Since the external route is required in the most extensive form of the disease, the book has also covered it extensively. This book is an indispensable resource for otorhinolaryngologists, ophthalmic surgeons, ophthalmic plastic surgeons, physicians, microbiologists, pathologists, radiologists, neurosurgeons, faciomaxillary surgeons and junior and senior consultants optometrists and students.Par Ruifang Sui, Fu Tang, Minglian Zhang. 2022
This book includes the concept, general summary and the equipment of the visual electrophysiological examination. It also covers the clinical…
application scope, diagnosis protocol, standardized operation steps, clinical report samples, and the key points of reading reports, etc. of visual evoked potential (VEP), electroretinogram (ERG), electrooculogram (EOG), multifocal VEP, multifocal ERG and other commonly used visual electrophysiological examinations. Typical clinical report examples of normal and abnormal waveforms are specially added, which is a highlight of this book and can help clinical technicians quickly grasp the key points of electrophysiological report reading.Despite differences in frequency causation and infectivity adenovirus epithelial keratitis and Thygeson s superficial punctate keratitis …
TSPK are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and coarse epithelial TSPK lesions This book presents the morphological features dynamics and sequelae of adenovirus and Thygeson s keratitides captured at high magnification in the living human cornea It thereby fills the existing void between conventional photographs and slit-lamp observations Case reports demonstrate the importance of patient history in differential diagnosis illustrate the need for familiarity with early manifestations of adenovirus infections and assist in the diagnosis of rare variants of TSPK Furthermore the detailed observations on the natural course of the diseases ensure that the book will serve not only as a diagnostic tool but also as a reference when evaluating the effects of potential new treatmentsPar Michael Perry. 2021
This book provides a practically applicable guide to injuries, diseases, and disorders affecting the head, neck, and dental region seen…
within accident and emergency departments. These regions contain a number of specialized structures each with individual neural, muscular and vascular elements, meaning that the study of these anatomical areas is complicated and often quite daunting. Chapters in this work aim to break the treatment of such injuries and diseases into an easy-to-digest format via chapters featuring a symptom-based approach. Therefore, enabling the reader to quickly access the information they require when treating patients with a variety of disorders in the emergency room. Diseases and Injuries to the Head, Face and Neck: A Guide to Diagnosis and Management is a concise overview of how to deal with head, neck, and dental emergencies and is an important up-to-date resource for all medical professionals and trainees who encounter these patients.Par Sarwar Zahid, Kari Branham, Dana Schlegel, Mark Pennesi, Michel Michaelides, John Heckenlively, Thiran Jayasundera. 2018
Classically photo atlases of retinal dystrophies have been divided into sections that describe and depict a particular retinal finding…
or disease after which a differential diagnosis of potential diseases or mutated genes is provided However given the rapid improvement in molecular diagnostics and the exponential increase in our understanding of the phenotypes caused by each mutated gene the paradigm has changed Physicians are now more interested in the variable expressivity associated with mutations in each individual gene Therefore Retinal Dystrophy Gene Atlas catalogs the different phenotypes that have been reported with each mutated gene Each section describes a gene and its known clinical phenotypes and features of disease along with retinal photos of affected patients Written by prominent retinal dystrophy specialists from the largest dystrophy centers worldwide Retinal Dystrophy Gene Atlas contains more than 80 chapters each of which describes the clinical and photographic manifestations of a specific gene The chapters include stunning clinical color photographs of the retina autofluorescence imaging electrophysiologic findings and cross-sectional imaging Retinal Dystrophy Gene Atlas serves as a resource to aid genetic diagnosis in patients with retinal dystrophiesPar Ahmad Aref, Rohit Varma. 2016
This text provides expert instruction on the techniques currently employed for the surgical treatment of glaucomatous disease covering both…
the host of novel microinvasive devices for treatment of milder stages and the refined strategies that enhance success rates in patients with advanced disease The critical steps in each procedure are clearly described with the aid of many high-quality illustrations and surgical videos Pearls and pitfalls of the various techniques are highlighted and helpful information is provided on indications preoperative considerations potential intra- and postoperative complications and strategies for reducing the incidence of such adverse events Each treatment method is addressed in a dedicated stand-alone chapter ensuring ease of reference for the practitioner Readers will find this book written by internationally recognized experts in the field to be an exceptional source of up-to-date information on advanced glaucoma surgical techniquesPar Thomas Reinhard, Frank Larkin. 2012
This book written by leading clinicians and scientists focuses on recent clinically relevant advances in the diagnosis and…
treatment of corneal disorders After an opening chapter considering the latest knowledge on the heredity of keratoconus important advances in corneal imaging are discussed in particular the use of optical coherence tomography and in vivo confocal microscopy for evaluation of the normal and the diseased cornea Antiangiogenic treatment options are then reviewed and new aspects in the diagnosis and therapy of mycobacterial keratitis explained Further chapters address the storage of donor cornea for penetrating and lamellar keratoplasty and the keratoplasty in infants The book closes by discussing new developments in antibacterial chemotherapy for bacterial keratitisA top expert reveals his insights into Meibomian gland dysfunction, a ubiquitous, misunderstood disease that leads to Dry Eye syndrome…
In Reversing Dry Eye Syndrome (Yale University Press 2007), ophthalmologist Steven Maskin introduced readers to Dry Eye syndrome, explaining what the syndrome is, why it occurs, and how it can best be managed and treated. In Your Dry Eye Mystery Solved, he reveals his recent discoveries and treatments for Meibomian gland dysfunction (MGD), an underlying disease that leads to Dry Eye syndrome and involves blockage of the oil-producing tear glands within the eyelids. Not only are these glands key to clear vision and comfortable eyes, but when disrupted they can cause severe pain and a host of related symptoms.This is a practical guide to using lasers in the Eye clinic and includes all commonly performed Lasers for a…
range of ocular conditions. It uses multiple illustrations of real-life fundus photographs, FFA images, OCT images and digitally modified retinal images to simplify learning the fundamentals of laser physics and physiology, laser safety and an overview of the variety of ophthalmic lasers in current use. It standardizes Laser procedures and serves as a reference guide for Ophthalmic trainees learning the technique that can be transferred to their clinical practice. The book simplifies understanding of Ophthalmic Lasers and answers common questions of how and why things are done. Key Features • Emphasizes on Nd-YAG Laser, Lasers in Glaucoma and Photothermal Lasers for Retinal Pathology, with clarity on techniques and pearls on dealing with common laser related issues that come with experience.• Provides content in a Q&A format which is ideal as a lesson from trainer to trainee and answers all the doubts and laser related questions a trainee may have and aids their learning and progression to performing Lasers safely and independently.• Uses digitally modified images with bullet points and reference text boxes, making the content user friendly and easy to understand.Par Pradeep Venkatesh. 2022
Vitreoretinal (VR) surgery has steadily evolved over the years and this handbook provides a comprehensive overview about its past, present…
and future. It covers a wide array of topics ranging from its fascinating origins to recent technological advances, from surface anatomy to their clinical relevance, from anaesthesia to building and maintenance of operation theatre, from major surgical steps to sub-steps, from preventing to managing complications, and from routine surgeries to rare surgeries. Included in addition is a section on futuristic surgeries and another on important studies in relation to vitreoretinal surgery. Hence, Handbook of Vitreoretinal Surgery serves as a ready reference for both fledgling and experienced VR surgeons in this exciting field of ophthalmic surgery. . Key Features Includes recent developments like 3D surgery, telescopic IOL, bionic implants and robotic surgery. Highlights the importance of surface anatomy and provides a deeper view into the working of vitreous machines, microscopes and other surgical components. Text is supported with videos of rare surgeries like endoillumination-assisted scleral buckling surgery, placement of retisert intravitreal implant, suprachoroidal drug injection, intralesional injection into a subretinal abscess and endoillumination-assisted biopsy of intraocular mass lesions.Par Richard Spaide, Alan Bird, Daniel Pauleikhoff, Frank Holz. 2012
Age-related macular degeneration is the most common cause for the loss of central vision beyond the age of 50 in…
industrial nations Triplication of the number of affected patients is expected over the next 25 years Especially over the last years the standard of knowledge regarding etiology risk factors diagnostics and therapy of this retina illness has substantially grown - this will be covered in this up-to-date multi-authored work Apart from epidemiologically and genetically identified risk factors both the various pathophysiological aspects including the role of the complement system and clinical manifestations including OCT and angiographic characteristics are clearly represented Furthermore the different therapeutic approaches are presented and discussed including proven procedures such as intravitreal anti-VEGF therapy and seeing-aid systems in addition to the latest and upcoming methods in the area of pharmacology The volume is well-illustrated and tables and summaries complete the presentationPar Alan Hall, Patrice Josset, Norbert Schrage, Harold Merle, Fran ois Burgher, Laurence Mathieu, Lucien Bodson, Max Gerard, J el Blomet. 2010
More than 25 000 chemical products have the potential to cause ocular burns Because such burns can result in…
loss of sight or the need for corneal transplantation they must be taken very seriously This book is the first to be devoted entirely to chemical ocular burns All aspects of the subject are covered including history epidemiology chemical agents and reactions histology pathophysiology clinical signs medical and surgical treatments and emergency care Particular attention is paid to the mechanisms involved in ocular burns and to the links between the chemical reactivity of corrosive agents and the clinical manifestations Current principles of decontamination are fully explained and the latest treatment techniques are discussed in detail This book stands at the interface of the chemical and medical sciences It will be of great practical value to ophthalmologists and doctors in emergency medical and burns units and will acquaint chemists with the clinical consequences of corrosivity