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This book discusses applications of pluripotent stem cells to study eye disease in vitro and to create novel therapies for…
degenerative eye diseases. Chapters are contributed by experts in the field and cover such topics as the use of pluripotent stem cells in 2D and 3D engineering of ocular tissues for disease modelling and drug testing as well as approaches to replace degenerated RPE and photoreceptors in macular degeneration and retinitis pigmentosa. Pluripotent Stem Cells in Eye Disease Therapy presents a comprehensive discussion of basic science and clinical applications and is an indispensable resource for everyone from advanced graduate students to advanced professionals who want to learn about the potential of stem cell biology and its role in the field of retinal diseases.Current Concepts in Ophthalmology
Par Andrzej Grzybowski. 2020
This book casts light on the most recent and significant changes and challenges in Ophthalmology over the last years. It…
provides essential and relevant new information and improvements on the main areas of Ophthalmology. Current Concepts of Ophthalmology elaborates on recent developments in Refractive and Cataract surgery, Cornea transplants, Neuro-Ophthalmology and many more. Based on increasing professional subject specialisation, this book offers the opportunity to stay up-to-date with areas outside of the own specific sub-specialty. Further, it traces issues and useful information to understand the trends and areas of future interest.Written by renowned experts of the respective fields, readers will discover a concise update on modern ophthalmology.Foundations of Corneal Disease: Past, Present and Future
Par Kathryn Colby, Reza Dana. 2020
The field of cornea has seen tremendous advances over the last 40 years—this uniquely comprehensive book will discuss the history…
of these advances, current best practices in important diseases of the cornea and ocular surface, and examine future directions in diagnosis and management. Written by leading experts, many of whom trained under Claes Henrik Dohlman, MD, PhD, whose influence and many invaluable contributions have defined and shaped the field of cornea, each chapter will reflect the state of the art in the various aspects of cornea. Foundations of Corneal Disease: Past, Present, and Future contains six different sections, opening with an introduction which delves into the evolution of subspecialty training in cornea, and provides a historical perspective of our understanding of ocular surface disease. Section Two addresses perspectives on important corneal and external diseases including infectious keratitis, dry eye, and herpes simplex. Section Three and Section Four address surgery and surgical alternatives, and frontiers in corneal research. Section Six closes this book with a discussion of special topics: imaging the cornea, corneal blindness, eye banking, and clinical trials in dry eye, and explores future directions in this fast-paced field. Foundations of Corneal Disease: Past, Present, and Future contains is an ideal guide for corneal specialists, ophthalmology residents and fellows planning to enter cornea, corneal scientists, and to those in ophthalmology and visual science interested in a comprehensive resource on cornea and the history of this field.Behçet Syndrome
Par Hasan Yazici, Yusuf Yazici, Gulen Hatemi, Emire Seyahi. 2020
The expanded second edition of this important work provides an up-to-date and comprehensive overview of Behçet syndrome. New and updated…
chapters focus on recent advances in the areas of pathogenesis, the microbiome, genetics and epigenetics, clustering of symptoms, disease assessment and new treatment options. The book examines how these developments have changed the way physicians approach diagnosis, treatment, and management of Behçet patients. It also analyzes the wide variety of clinical manifestations of the disease including mucocutaneous lesions, intraocular inflammation, central nervous system involvement, deep vein thrombosis and other forms of major vascular disease. Building on the success of its predecessor, the Second Edition of Behçet Syndrome is an invaluable resource for physicians, residents, fellows, and graduate students in rheumatology, dermatology, ophthalmology, neurology, gastroenterology, and internal medicine.Darwin’s Challenge Answered: Darwin’s theory as Darwin stated, “absolutely breaks down”
Par J. Jay Rigney, O.D.. 2017
Darwin's book The Origin of Species was published in 1859. On page 159 of his book Darwin states, “If it…
could be demonstrated that any complex organ existed, which could not possibly have been formed by numerous, successive, slight modifications, my theory would absolutely break down”. This book directly, specifically, decisively answers Darwin's Challenge. As a result Darwin's theory as Darwin himself stated, "absolutely breaks down". Dr. Jan Jay Rigney graduated from Northeastern State University in Tahlequah, Oklahoma in 1984. At the time of the writing of this book, he will have been in private practice Optometry for thirty-one years. While practicing Optometry, he has had the opportunity to daily, for over 35 years, observe the design, function, and intricate interworkings of the human eye.Neuro-ophthalmic Disorders (Current Practices in Ophthalmology)
Par Preeti Patil Chhablani. 2020
This book discusses in detail the major advances in the field of neuro-ophthalmology. Based on the latest research from across…
the globe, it highlights recent developments in all areas of neuro-ophthalmology, including optic neuritis and the associated demyelinating diseases – especially the changing paradigms in the diagnosis and management of multiple sclerosis and neuromyelitis optica. It also covers the various types of hereditary optic neuropathies as well as nystagmus and its management. In order to provide comprehensive information in a single volume, it addresses topics of interest in pediatric neuro-ophthalmology, such as pediatric optic neuritis and cortical visual impairment, innovations in the management of ocular motility disorders and other disorders of the optic nerve and central nervous system, including ischemic neuropathies and idiopathic intracranial hypertension.This book provides a one-stop source of information on all key topics of neuro-ophthalmology, enabling trainee fellows and practitioners to keep abreast of the current thoughts in this field.As part of the series “Current Practices in Ophthalmology” this volume is intended for residents and fellows-in-training, as well as generalist and specialist ophthalmologists alike.Inflammatory and Infectious Ocular Disorders (Retina Atlas)
Par Hyeong Gon Yu. 2020
This atlas covers most ocular inflammatory and infectious diseases of importance with clinical significance. It includes chapters on non-infectious diseases…
and chapters on infectious diseases. For each chapter, essential information regarding the clinical features, diagnosis, and management is described in the text based on the up-to-date knowledge, and more than 240 carefully selected photographs are provided. World-famous experts in this field have included as many as valuable photographs of patients as possible. New imaging tests of ultra-wide field retinal images and high-resolution optical coherence tomography are included in addition to conventional fundus photos and fluorescein angiographs. Especially, chapters on infectious diseases provide invaluable photos of rare but clinically important diseases. Designed to assist in the diagnosis and treatment of ocular inflammation and infection, this book is meant for the retina specialist, researchers of ocular inflammation, general ophthalmologist, resident and retina fellow. Inflammatory and Infectious Ocular Disorders atlas is one of the nine volumes of the series Retina Atlas. This series provides global perspective on vitreoretinal diseases, covering imaging basics, retinal vascular disease, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, surgical retina, ocular oncology, pediatric retina and trauma. This comprehensive atlas is spread over 9 volumes and about 100 chapters, covering validated and comprehensive information on retinal disorders.Multifocal Intraocular Lenses: The Art and the Practice (Essentials in Ophthalmology)
Par Jorge L. Alió, Joseph Pikkel. 2019
This comprehensive 2nd edition will build on the highly successful first edition, providing an updated global perspective of the fundamentals…
of multifocal intraocular lenses. The varying outcomes, limitations, and the neuroadaptation process necessary for an adequate clinical success are thoroughly discussed, along with an overview of the different types of multifocal lenses, including the recently developed extended depth of focus lenses.Multifocal Intraocular Lenses: The Art and the Practice, 2nd edition opens with an introduction that will delve into current technological offerings for the correction of pseudophakic presbyopia, as well as the opportunity for refractive lens exchange in advanced presbyopic ages and the opportunity to use these lenses. The first section will include the historical background and clinical indications, while section two addresses the varying types and models of lenses currently available, including important clinical and technological highlights. Section three and four will follow, and provide an extended look at the Zeiss and Alcon Family Multifocal IOL’s. Section five will delve into extended depth of field lenses, and will contain an introduction about the concept, different models and the evidence available about their outcomes. Section six concludes the book, closely examining accommodative intraocular lenses, and a full update will be provided on these lenses, the failures of the past and the hopes for the future. Multifocal Intraocular Lenses: The Art and the Practice, 2nd edition is a thorough, resource for the practical ophthalmologist and ophthalmic surgeon interested in learning more about intraocular lenses, identifying the best technologies and lenses for the benefit of their patients.Trauma and Miscellaneous Disorders in Retina (Retina Atlas)
Par Eduardo Büchele Rodrigues, Carsten Helmut Meyer, Eduardo Tomazoni. 2020
This atlas presents common and rare traumatic conditions of the retina and related intraocular tissues (choroidal rupture, commotio retinae, intraocular…
foreign body). It also covers intraocular tumors and congenital conditions such as myelinated retinal nerve fibers. Including numerous high-quality figures using various modalities, the book reviews the basic management principles in a reader-friendly style to help readers gain a better understanding of the diseases discussed.Trauma and Miscellaneous Disorders in Retina is one of nine volumes in the series Retina Atlas. This series provides comprehensive information on vitreoretinal diseases, covering imaging basics, retinal vascular disease, ocular inflammatory disease, retinal degeneration, retinal surgery, macular disorders, ocular oncology, pediatric retina and trauma.Current Advances in Ophthalmic Technology (Current Practices in Ophthalmology)
Par Parul Ichhpujani. 2020
This book provides an overview of the latest technological advances in various ophthalmology subspecialties: from the latest glaucoma shunt devices…
to mobile adaptors for posterior segment evaluation, this book has it all. It gives readers a valuable head start for adopting the uber-new and cutting-edge products now available on the market. Being familiar with these new products and technologies will help both new and established ophthalmologists make effective and efficient choices, while also helping their practices stand out from the crowd. Perhaps no other branch of medicine is as technology-oriented as ophthalmology: be it lasers, fiber optics, robotics, stem cells or nanoparticles, every cutting-edge step that “Research and Development” takes is rapidly integrated into everyday eye practice.As part of the series “Current Practices in Ophthalmology”, this volume is intended for residents, fellows-in-training, generalist ophthalmologists, specialists and vision science researchers alike.OCT and Imaging in Central Nervous System Diseases: The Eye as a Window to the Brain
Par Andrzej Grzybowski, Piero Barboni. 2020
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading…
neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models.Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.Simplifying Strabismus: A Practical Approach to Diagnosis and Management
Par Saurabh Jain. 2019
This book provides a clear, concise and easy to understand guide to the diagnosis and management of strabismus. Throughout the…
text, a practical approach to examining, diagnosing and treating patients with strabismus is utilised, supported with case studies in the form of patient photographs and ocular motility videos. Flowcharts and tables are included, together with evidence based management plans and suggestions for further reading. Simplifying Strabismus: A Practical Approach to Diagnosis and Management is aimed at optometrists, junior and senior ophthalmologists, as well as any medical professional wishing to improve their knowledge of strabismus.Retinal Degenerative Diseases: Mechanisms and Experimental Therapy (Advances in Experimental Medicine and Biology #1185)
Par Joe G. Hollyfield, Robert E. Anderson, Christian Grimm, John D. Ash, Catherine Bowes Rickman, Matthew M. LaVail. 2019
This book contains the proceedings of the XVIII International Symposium on Retinal Degeneration (RD2018). A majority of those who spoke…
and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium focused on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the “best” and “most important” meetings in the field. The volume presents representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. While advances in these areas of retinal degenerations were described, there will be many new topics that either are in their infancy or did not exist at the time of the last RD Symposium, RD2016. These include the role of inflammation and immunity, as well as other basic mechanisms, in age-related macular degeneration, several new aspects of gene therapy, and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those were reported at the RD2016 meeting and included in the current volume. We anticipate the excitement of those working in the field and those afflicted with retinal degenerations is reflected in the volume.Retinal Pigment Epithelium in Health and Disease
Par Alexa Karina Klettner, Stefan Dithmar. 2020
This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium…
(RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development of RPE in diagnostics and therapy are covered, as well as some practical knowledge about RPE experimental models. Retinal Pigment Epithelium in Health and Disease highlights new findings of RPE research and includes the state-of-the-art knowledge of each RPE topic presented. This important feature sets this book apart from other publications, with the chapters following a design which leads from the general to the specific, to give a precise collection of the facts known. The chapters are written by well-known experts that are currently active in the field as consultants, basic scientists, and group leaders, providing expert guidance on the current aspects and future outlooks of this topic.Treatment of Non-infectious Uveitis
Par Phoebe Lin, Eric Suhler. 2019
This unique, comprehensive book provides a much-needed reference on the treatment and management of non-infectious uveitis. Carefully designed, Treatment of…
Non-infectious Uveitis is the first book of its kind to provide an in-depth, clinically-relevant, expert-driven resource for ophthalmologists focusing on modalities of uveitis treatment, their mechanism of action, dosing, and side effects.Each chapter provides an introduction, mechanism of action, indication, dosage, side effects, and efficacy summaries from clinical trials and other published literature. Topics range from topical treatment, to locally administered therapy including drug-releasing implants, to systemic immunosuppressive treatments both tried and new, as well as surgical management, with each chapter highlighting important practice pearls as well as easy-reference dosing tables, side effects, and lab monitoring pertinent to the agents discussed. The book concludes with a discussion of novel approaches to the treatment of non-infectious uveitis, and special considerations when treating uveitis in the pediatric patient. The majority of patients with non-infectious uveitis are treated by comprehensive ophthalmologists, many of whom are less familiar with established treatment guidelines outlining the role of corticosteroids and immunomodulatory therapy. While the non-specialist, resident, or fellow is sure to benefit from this one-stop guide to uveitis treatment, retina and uveitis specialists alike will also appreciate the practice tips and thorough coverage of this expertly-written reference. Treatment of Non-infectious Uveitis is the ideal reference for all ophthalmologists who seek to improve their understanding of the causes of uveitis and learn how to best treat this condition.Surgical Retina (Retina Atlas)
Par Masahito Ohji. 2019
This atlas presents the state-of-the-art in vitreoretinal surgery. In ten chapters written by internationally respected vitreoretinal surgeons, it addresses various…
surgical diseases of the retina and vitreous, providing detailed information on all key surgical aspects. The topics covered include small-gauge vitrectomy and surgical aspects of retinal detachment, proliferative vitreoretinopathy, proliferative diabetic retinopathy, serous macular detachment with optic disc pit, coloboma of the choroid, and cysticercosis. Surgical aspects of various macular diseases such as epiretinal membrane, vitreomacular traction syndrome, and macular hole are also examined. Given its scope, the book offers a valuable asset for practicing ophthalmologists, vitreoretinal specialists, and trainees in the field. The Surgical Retina Atlas is one of nine volumes in the series Retina Atlas, which provides comprehensive and validated information on vitreoretinal diseases, covering imaging basics, retinal vascular disease, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, surgical retina, ocular oncology, pediatric retina and trauma.Ocular Oncology (Retina Atlas)
Par Duangnate Rojanaporn. 2019
This atlas covers all aspects of retina, retinal pigment epithelium, and choroidal tumors, as well as other simulating lesions of…
intraocular tumors and paraneoplastic syndromes. Each chapter features numerous high-quality pictures based on multimodal imaging, including color fundus photography, fundus autofluorescence, optical coherence tomography, ultrasonography, ultra-widefield imaging, and fundus angiography. Designed to assist in the diagnosis and treatment of posterior segment intraocular tumors and simulating lesions, this book is intended for ocular oncologists, retina specialists, general ophthalmologists, residents and retina fellows. Ocular Oncology atlas is part of the series Retina Atlas, which provides global perspectives on vitreoretinal diseases, covering imaging basics, retinal vascular disease, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, surgical retina, ocular oncology, pediatric retina and trauma. Retina Atlas consists of 9 volumes and about 100 chapters, presenting validated and comprehensive information on retinal disorders.Retinal Optical Coherence Tomography Image Analysis (Biological and Medical Physics, Biomedical Engineering)
Par Xinjian Chen, Fei Shi, Haoyu Chen. 2019
This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in…
the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image processing, pattern recognition and machine learning methods to real clinical data. It is a valuable resource for researchers in both medical image processing and ophthalmic imaging.Integrative Ophthalmology (Advances in Visual Science and Eye Diseases #3)
Par Ningli Wang. 2020
With the development of nature science and industrial technology, more and more patients are benefitting from the rapid progress in…
ophthalmology, as the use of new medicine and delicate surgical therapy has ensured them the chance to restore their sight. However, some problems have come up during its development, of which the most serious one is the limitation of the ophthalmology. Eyes are not isolated organs, they are connected to our body, and thus, the general status of our body will affect the eyes’ function. Therefore, it is of great importance that the ophthalmologists see the big picture while dealing with the clinical problems. Based on the above observations, we put forward the concept of Integrative Ophthalmology, and describe the ophthalmology related medical situations that are prone to be neglected in clinical practice in a bid to increase the awareness of doctors from all fields that a holistic view should be adopted in clinical practice, and it is the patients that we are treating rather than the disease. There are 9 parts in the book, containing the concept of integrative ophthalmology, intraocular and intracranial pressure gradient related diseases,and the relationship between the different general status and eye disorders. We do believe that the integrative ophthalmology is the key to the development of ophthalmology and hope readers can benefit from this book.Oculofacial, Orbital, and Lacrimal Surgery: A Compendium
Par Adam J. Cohen, Cat Nguyen Burkat. 2019
This comprehensive text covers both core and advanced principles within oculofacial, orbital, and lacrimal surgery with extensive detail not found…
in any other current book on the subject. Richly illustrated with hundreds of images,Oculofacial, Orbital, and Lacrimal Surgery: A Compendium is written and edited by international leaders in fields spanning ophthalmology, otolaryngology, oral and maxillofacial surgery, and plastic surgery. Covering topics such as embryology, anatomy, and physiology of the lacrimal system, imaging for orbital diseases and thyroid-related ophthalmology, and flap geometry and planning, this book is an excellent resource for those in training, as well as seasoned clinicians looking to stay current. This book is divided into five sections: Eyelid, Oculofacial, Lacrimal, Orbit, and Socket, with each section containing detailed chapters addressing evaluation, imaging, and various surgical approaches and management.Designed to not only provide an anatomical and surgical guide for all three types of surgeries, but to help physicians avoid mistakes and correct complications of patients referred to them, Oculofacial, Orbital, and Lacrimal Surgery: A Compendium is the definitive, authoritative reference on this complex field.