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Eddie Olczyk: Beating the Odds in Hockey and in Life
Par Eddie Olczyk, Perry Lefko. 2019
Eddie Olczyk had built a life and career most people could only dream of. Growing up in the suburbs of…
Chicago, he fell in love with the game of hockey during an era when most kids preferred balls to pucks. Against all odds, he played on the 1984 U.S. Olympic hockey team as a 17-year-old, and four months later he was drafted in the first round by his hometown Chicago Blackhawks. During an illustrious 16-year career, he played for and alongside some of the greatest franchises and players in history, winning a Stanley Cup with the unforgettable 1994 New York Rangers. Years later, he coached former teammate Mario Lemieux and Sidney Crosby on the Pittsburgh Penguins before transitioning into the broadcast booth, where he has become one of the most recognizable voices of the sport. He then combined his skills as an analyst with his second passion— horse racing—and became an integral part of NBC’s coverage of thoroughbreds. Away from the spotlight, Olczyk and his wife of three decades raised four adoring children. He was respected and admired by fans, friends, and peers. Life was sweet. Then, at 7:07 pm on August 4, 2017, his entire world turned upside down. In Eddie Olczyk: Beating the Odds in Hockey and in Life, one of the biggest names in American hockey has written an inspiring and entertaining memoir of his life both on and off the ice. From shooting hundreds of tennis balls at a goal in his childhood living room to the ups and downs of his improbable hockey career to rollicking stories from the booth and the backstretch, Olczyk guides readers on his journey toward his ultimate test: a battle against Stage 3 colon cancer. For years, Olczyk’s goal was to be the best husband, father, broadcaster, and handicapper he could be. Today he has a new one: to bring as much awareness and support to those fighting cancer as he possibly can. In this emotional but often hilarious autobiography, you’ll learn why the people who know Eddie Olczyk best might describe him as “tremendously tremendous.”The Plant Paradox: The Hidden Dangers in "Healthy" Foods That Cause Disease and Weight Gain (The Plant Paradox #1)
Par Dr Steven R Gundry. 2017
From renowned cardiac surgeon Steven R. Gundry, MD, the New York Times bestselling The Plant Paradox is a revolutionary look…
at the hidden compounds in "healthy" foods like fruit, vegetables, and whole grains that are causing us to gain weight and develop chronic disease.Most of us have heard of gluten—a protein found in wheat that causes widespread inflammation in the body. Americans spend billions of dollars on gluten-free diets in an effort to protect their health. But what if we’ve been missing the root of the problem? In The Plant Paradox, renowned cardiologist Dr. Steven Gundry reveals that gluten is just one variety of a common, and highly toxic, plant-based protein called lectin. Lectins are found not only in grains like wheat but also in the “gluten-free” foods most of us commonly regard as healthy, including many fruits, vegetables, nuts, beans, and conventional dairy products. These proteins, which are found in the seeds, grains, skins, rinds, and leaves of plants, are designed by nature to protect them from predators (including humans). Once ingested, they incite a kind of chemical warfare in our bodies, causing inflammatory reactions that can lead to weight gain and serious health conditions.At his waitlist-only clinics in California, Dr. Gundry has successfully treated tens of thousands of patients suffering from autoimmune disorders, diabetes, leaky gut syndrome, heart disease, and neurodegenerative diseases with a protocol that detoxes the cells, repairs the gut, and nourishes the body. Now, in The Plant Paradox, he shares this clinically proven program with readers around the world.The simple (and daunting) fact is, lectins are everywhere. Thankfully, Dr. Gundry offers simple hacks we easily can employ to avoid them, including:Peel your veggies. Most of the lectins are contained in the skin and seeds of plants; simply peeling and de-seeding vegetables (like tomatoes and peppers) reduces their lectin content.Shop for fruit in season. Fruit contain fewer lectins when ripe, so eating apples, berries, and other lectin-containing fruits at the peak of ripeness helps minimize your lectin consumption.Swap your brown rice for white. Whole grains and seeds with hard outer coatings are designed by nature to cause digestive distress—and are full of lectins.With a full list of lectin-containing foods and simple substitutes for each, a step-by-step detox and eating plan, and delicious lectin-free recipes, The Plant Paradox illuminates the hidden dangers lurking in your salad bowl—and shows you how to eat whole foods in a whole new way.From bestselling author Dr. Steven Gundry, a quick and easy guide to The Plant Paradox program that gives readers the…
tools to enjoy the benefits of lectin-free eating in just 30 days.In Dr. Steven Gundry’s breakout bestseller The Plant Paradox, readers learned the surprising truth about foods that have long been regarded as healthy. Lectins—a type of protein found in fruits, vegetables, legumes, dairy, and grains—wreak havoc on the gut, creating systemic inflammation and laying the groundwork for disease and weight gain. Avoiding lectins offers incredible health benefits but requires a significant lifestyle change—one that, for many people, can feel overwhelming.Now, in The Plant Paradox Quick and Easy, Dr. Gundry makes it simpler than ever to go lectin free. His 30-day challenge offers incentives, support, and results along with a toolkit for success. With grocery lists, meal plans, time-saving cooking strategies, all-new recipes, and guidance for families and those following specialized diets (including ketogenic and vegan), The Plant Paradox Quick and Easy is the all-in-one resource Plant Paradox fans and newcomers alike need to jumpstart results reap the health benefits of living lectin-free.The Energy Paradox: What to Do When Your Get-Up-and-Go Has Got Up and Gone (The Plant Paradox #6)
Par Dr Steven R Gundry. 2021
The author of the bestselling Plant Paradox series takes a fresh look at one of the top health issues plaguing…
Americans—fatigue—and offers a revolutionary plan for boosting energy and revitalizing mental and physical stamina.In his bestselling books, The Plant Paradox and The Longevity Paradox, Dr. Steven R. Gundry offered game-changing perspectives on our wellbeing. In The Energy Paradox, Dr. Gundry expands upon his previous discussions of gut, microbiome, and mitochondrial health, linking immune malfunction to the mental and physical symptoms of fatigue—including exhaustion, brain fog, depression, anxiety, and low metabolism.As Dr. Gundry explains, feeling tired, moody, and zapped of energy is not normal, no matter your workload or age. Fatigue is an SOS flare from the body, one that is intended to alert us that something is wrong. In his clinical work, Dr. Gundry has found that his patients who complain of feeling sick and tired all the time almost always have something in common: the inflammation markers of a leaky gut.In The Energy Paradox, Dr. Gundry will offer readers the information and tools necessary to quiet the autoimmune battle raging within—a battle that depletes precious energy reserves, leaving you drained and prone to mood disorders and weight gain. With new guidelines on how to increase mitochondrial energy production and nourish the microbiome; 30 new Plant Paradox-approved recipes; and lists of energy-boosting foods to consume and energy-depleting foods to avoid, The Energy Paradox will help readers take back their lives, giving them the energy they need to feel, look, and be their best.From the author of the New York Times bestselling Plant Paradox series comes this revolutionary take on the keto diet…
that debunks common myths and shows readers how to reap the rewards of keto with less restrictionLike many doctors and nutrition experts, bestselling author Dr. Steven Gundry has long endorsed the ketogenic diet—a style of eating that heavily restricts carbohydrate intake to make the body burn fat for fuel. Because ketosis offers a variety of health benefits, including weight loss, reduced risk of illness, and enhanced energy, Dr. Gundry believed his patients’ efforts to adhere to the challenging regimen was worthwhile. That is, until his research uncovered a shocking truth: We’ve gotten keto all wrong.In Unlocking the Keto Code, Dr. Gundry reveals the biological mechanism that makes keto diets so successful: a cellular process known as “mitochondrial uncoupling.” As it turns out, ketones are not the magical fuel source they’ve been made out to be; in fact, the body cannot run on ketones and fats alone. Over the long term, a very low carb-diet can lead to muscle wasting and poor cognitive health. Luckily, you don’t have to restrict all carbs to reap the benefits of ketosis; you simply have to have enough ketones and other plant compounds called polyphenols present in your body to “unlock” the process of mitochondrial uncoupling. In this insightful, empowering, eminently practical book. Dr. Gundry explains the many ways readers can ignite this process, from feasting on plant-based foods (carbs that are typically off-limits on a keto diet!) to enjoying ketone generating foods such as goat and sheep milk products, to implementing a timed eating schedule. You will even discover the real reason how superfoods, even apple cider vinegar, work their magic; and its not what they you think!Grounded in cutting-edge science, this is the book for all the people who have tried and failed on a keto diet; for vegetarians and vegans who want to go keto; and for anyone who wants to lose weight and enjoy better health while eating a wide variety of foods. With food lists, hacks, and all-new recipes, Unlocking the Keto Code makes going keto easy and enjoyable for the first time.Family Engagement in Mental Health Interventions for Young Children (Springer Series on Child and Family Studies)
Par Laura Nabors, Jessica Dym Bartlett. 2023
This book examines the critical nature of engaging families in mental health interventions that promote well-being and resilience in young…
children, from birth to 8 years of age, with a particular focus on the importance of equity and systems of care. It addresses evidence-based and evidence-informed interventions to promote family engagement to improve behavioral, social, and emotional functioning of infants and toddlers, preschoolers, and children in the early elementary school years. The book is grounded in empirical knowledge on reducing health disparities and promoting equity in mental health care for young children, including equitable access, services, and outcomes. It emphasizes a community-based systems of care approach to family engagement in mental health interventions and highlights the most promising policies and practices.Key areas of coverage include:Mental health interventions for different developmental levels, including infancy and toddlerhood, the preschool years, and in early elementary school.Inequities and gaps in systems of care for young children.Evidence-based and evidence-informed prevention practices and intervention strategies to engage families and support children’s psychological well-being.Family engagement in interventions for young children with special needs or who are recovering from trauma. Family Engagement in Mental Health Interventions for Young Children is a must-have resource for researchers, professors, and graduate students as well as clinicians, therapists, and other professionals in developmental psychology, child and adolescent psychiatry, family and systems therapy, school and clinical child psychology, social work and counseling, pediatrics and school nursing, and all interrelated disciplines.Role of Microbes in Sustainable Development: Human Health and Diseases
Par R. C. Sobti, Ramesh Chander Kuhad, Rup Lal, Praveen Rishi. 2023
This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic…
manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, including proteins, enzymes, immunotoxins and secondary metabolites, that target cancer cells and cause tumour regression. The chapters also discuss the critical role of gut microbiota dysbiosis in the pathogenesis of autoimmune disease and in bowel-related diseases. Towards the end, the book explores the role of intestinal microbiota in metabolic health and the pathogenesis of common metabolic disorders. It presents state-of-the-art insights into important aspects of United Nations—Sustainable Developmental Goal 3.A History of Discoveries on Hearing (Springer Handbook of Auditory Research #77)
Par Darlene R. Ketten, Allison B. Coffin, Richard R. Fay, Arthur N. Popper. 2024
This volume focuses on the history of research on hearing from comparative approaches. Each chapters examines the most formative studies…
that led to current understanding of hearing across taxa and still influence hearing research in general. Much of the early work on hearing, which goes back to Aristotle, as well as the classic work of 16th to early 20th century scientists (e.g., Spellanzani, Retzius, Ramón y Cajal, and Helmholtz) is not well known to modern investigators. Similarly, work in the first 75 years of the 20th century is also unknown or, in some cases, dismissed because it is “old.” Much of the earlier work describes research approaches and results fundamental to our understanding of hearing as well as the beauty of observation and synthesis. The pioneering work on hearing contains ideas and questions that are still germane today. Thus, the goal of this volume is to introduce, review, and put into perspective, older but exemplary, extraordinary studies by investigators that form the basis of our knowledge as well as questions being asked today.Each chapter includes the first significant observations and approaches to hearing in the taxa and/or hearing type that is the focus of the chapter with some of the most important earlier papers discussed in some detail, including the theories, formative experiments, results, and conclusions. Each chapter provides briefer notations and citations of additional important papers that are outgrowths of the founding research – or correlate and even reverse the original works. This volume is a departure from the classic approach established for the SHAR books in which the focus has been on a single topic, and on the most recent and exciting discoveries. One difference in this volume from past SHAR volumes is that we have a more coordinated approach for the chapters to ensure that this volume is, indeed, a documentation of hearing research history, not a review of the latest status of the topic. A second difference is that the focus of the volume is on the historical value of studies. In that sense, the volume maintains the tutorial value for which SHAR books are famous, but it explores the ancestry of modern research in order to help new researchers to gain perspective on important questions and on fundamental information they may not fully appreciate – to their loss. Our interest in doing this volume comes from phenomena familiar to most senior investigators - that younger investigators often have little or no sense of the history of their discipline, and they often do not know that their “hot” new idea was not only pursued, and often solved, but further that it was solved in an elegant way. We believe it is important to bring the methodologies and discoveries on hearing done before the advent of the internet to light, for the benefit and growth of new research.In deciding on the chapter divisions for this book, we considered a number of different organizational schemes, and particularly using as a focus methodological approaches (e.g., psychoacoustics, low to high frequency types, physiology, anatomy). However, we came to the conclusion that most investigators tend to be more focused on working within a particular taxonomic group, settling on particular taxa, in many cases driven by the special hearing abilities. We also concluded that that this approach is more naturally related to the evolution not only of hearing, but also to the evolution of ideas, as much of hearing science was part of the “natural philosopher” approach that was a core element of historical discoveries.CT Colonography for Radiographers: A Guide to Performance and Image Interpretation
Par Joel H. Bortz, Aarthi Ramlaul, Leonie Munro. 2023
This second edition, comprising 28 chapters, explains every aspect of the role of radiographers in performing CT colonography (CTC) and…
interpreting CTC images with the aim of enabling radiographers to extend the scope of their practice. It provides information required with respect to communication with the patient, procurement of informed consent, the principles of CT as well as dual-energy CT and photon counting CT, radiation dose, patient preparation and positioning, the use of contrast media, the performance of diagnostic and screening CTC studies, the interpretation and reporting of images, legal and professional requirements, and the importance of clinical audits.A wide range of CTC findings is described and depicted, covering normal anatomy, artefacts, haemorrhoids, polyps, colon cancer, diverticular disease, lipomas, extracolonic structures, opportunistic screening for osteoporosis and metabolic associated fatty disease, and CTC in incomplete or failed colonoscopy. The role of other modalities such as ultrasound, magnetic resonance imaging, and nuclear medicine in colorectal cancer patients is discussed. In addition, the text covers the role of artificial intelligence and machine learning in imaging of the colon for the detection of polyps, diagnosis and staging of colorectal cancer. Lastly, a chapter focusing on self-assessment of image interpretation will aid learning.This book provides the support that radiographers need in order to perform CTC studies to the standard required in terms of advances in imaging and interpretation of images.This book provides up-to-date guidance on how to recognize and reduce trauma-based dissociation. Through a therapist-guided approach, readers will increase…
their awareness of their own experiences of dissociation and develop strategies for reducing these responses, with an overall goal of feeling more connected within themselves and with others. Trauma-based dissociation usually first occurs during a very threatening situation from which there is no physical escape. The dissociative response happens automatically for protection outside of awareness, so the person doesn’t realize what they were doing. This protective response can happen again when other concerning situations occur, and eventually develop into an automatic response to perceived threats. Disconnecting to Survive: Understanding and Recovering from Trauma-based Dissociation is a guide for individuals who experience dissociation or wonder if they do, and for their family, friends, and professionals who want to help them. Several unique features of this book make it valuable as a therapeutic experience for trauma survivors as well as a useful resource for professionals. "Check-ins” throughout the book provide an in-the-moment experience of self-monitoring and pacing while reading. Frequent case examples enhance understanding of the ideas described and validate the experiences of readers who have persevered through traumatic life situations. A section at the end of each chapter provides opportunity to explore how the concepts apply to the reader. Readers also will learn about a three-phase model for determining their present needs and their readiness for different interventions based on their phase of trauma recovery. In addition to physical, emotional, and sexual abuse, other types of interpersonal trauma are delineated, including race-based trauma, religious trauma, medical trauma, emotional neglect, military-related trauma, and mistreatment due to sexual orientation. In addition, a chapter is devoted to each of the important topics of dissociation in children and the relationship between trauma, dissociation, and psychosis.Targeting Epigenetics in Inflammatory Lung Diseases
Par Gaurav Gupta, Brian G. Oliver, Kamal Dua, Md Khadem Ali, Piyush Dave. 2023
This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer,…
pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.Chromium in Plants and Environment (Environmental Science and Engineering)
Par Nitish Kumar, Clemens Walther, Dharmendra K. Gupta. 2023
This edited book brings together a diverse group of environmental science, sustainability, and health researchers to address the challenges posed…
by global mass poisoning caused by chromium contamination of soil and plants. In recent years, contamination of the environment by chromium has become a major concern. Chromium is a non-degradable, harmful, and toxic pollutant which negatively affects the environment. It is unique among the heavy metals found in industrial wastewater and sewage and sludge, as it may exist as a trivalent cation and as anion in the hexavalent state in the pH range of agricultural soils. It is used on a large scale in many different industries, including metallurgy, electroplating, production of paints and pigments, tanning, wood preservation, chemical production, and pulp and paper production. These industries are contributing larger amount of chromium, which can ultimately have significant adverse effects on biological and ecological activities of ecosystem. Chromium enters the food chain through consumption of plant material. A high concentration of chromium has been found to be harmful to vegetation. As the chromium concentration in plants increases, it adversely affects several biological parameters and eventually renders the soil barren.The book sheds light on this global environmental issue and proposes solutions to contamination through multi-disciplinary approaches and case studies from different parts of the world.This book is a valuable resource to students, academicians, researchers, and environmental professionals who are doing field work on chromium contamination throughout the world.The New Futures of Exclusion: Life in the Covid-19 Aftermath
Par Daniel Briggs, Luke Telford, Anthony Lloyd, Anthony Ellis. 2023
Based upon global data and following on from Lockdown: Social Harm in the COVID-19 Era, this book discusses the rise of surveillance…
capitalism and new forms of control and exclusion throughout the Covid-19 pandemic. It particularly addresses the use of vaccine passports, mandates and the new forms of capital extraction and political control that emerged throughout the pandemic. The book also explicates how the ‘vaccine hesitant’ became marginalized in both mainstream discourse and through regulatory interventions. Whilst the book addresses the wider political economy within which so-called ‘anti-vaxxers’ were ostracized, it also explores the complex nature of their sentiments. The book closes by considering The New Futures of Exclusion, outlining the forms of surveillance and control that may be implemented in the future particularly in light of the challenges brought by global warming and the energy transition. It is a broadly accessible text, particularly appealing to policymakers, general readers and academics in sociology, political sociology, politics, human geography, political economy, criminology, social policy, psychology, history, and infectious diseases and medicine.Biomarkers in Neuropsychiatry: A Primer
Par Antonio L. Teixeira, Natalia P. Rocha, Michael Berk. 2023
This book presents the ‘state of the art’ of biomarkers research in neuropsychiatric conditions, from dementia to eating disorders, as…
well as providing methodological, practical and ethical issues related to the development of biomarkers. Biomarkers have revolutionized clinical research and practice in most fields of medicine, but psychiatry has lagged behind. However, in the last decade, there has been a growing expectation that biomarkers will advance and, ultimately, reframe psychiatry research and practice. Biomarkers might inform about diagnosis, therapeutics, prognosis, contributing to a ‘personalized medicine’. Understanding their meaning, possibilities and limitations will help clinicians, researchers and students in the related areas navigate and excel in the challenging and ever changing field of neuropsychiatric disorders.This book explores the shifting nature of physician–patient relationship in China. Specifically, it takes the physician–patient relationship during the barefoot…
doctor program in 1968–1978, the marketization of healthcare in 1978–2002, and the healthcare reform in 2003–2020 as three historical periods, illustrating how the nature of the physician–patient relationship has changed over time. Analyzing the ways in which law and social policies—involving the doctrine of informed consent, public hospital reform, and systemic healthcare reform—have in different ways shaped and changed the practices of physicians and patients, which illustrates how the bond between them threatens to collapse. With a uniquely vivid depiction of Chinese healthcare issues, this book will interest sociologists, China scholars and more.Approaches for Science Illustration and Communication (Biomedical Visualization #4)
Par Mark Roughley. 2023
This edited book explores the breadth of approaches undertaken by scientists, artists and communicators in their crucial role making science…
accessible, engaging and impactful. Contemporary approaches in science illustration and visualization include a variety of creative methodologies that are valuable for effective communication, teaching, learning and professional practice. These range in method from anatomical drawings used in medical curricula, to 2D animations and editorial illustrations available in the public realm. They also include unexpected approaches such as the use of tabletop board games, comics and collage in understanding our bodies, emergent health threats and cutting-edge science developments. If you are a scientist seeking to enhance your ability to communicate your research or an artist interested in biomedical visualization, this volume serves as an introduction to contemporary approaches in science illustration and communication. By understanding the creative methods and techniques employed in this field, we can collectively work towards fostering a deeper appreciation of art in science, and continue to captivate and inspire audiences worldwide.FND Stories: Personal and Professional Experiences of Functional Neurological Disorder
Par Gregg H. Rawlings, Markus Reuber, Jon Stone and Maxanne McCormick. 2024
Functional Neurological Disorder (FND) is one of the most common diagnoses among patients referred to neurology clinics, but is still…
misunderstood and under-recognised by medical professionals and the public. This vital book brings together the voices of healthcare professionals and people living with FND across the world. Experts in neurology provide a clear, evidence-based explanation of FND as an introduction, laying the foundation for the personal stories of people with FND and the professionals involved in their care. From testing and diagnosis to dealing with stigma and coping with changing symptoms, each chapter delves into the realities of life with FND from the perspective of lived experience. FND can be an isolating condition. The life stories in this book will help you to make sense of living with FND and tackle its challenges alongside others with the condition.Human iPSC-derived Disease Models for Drug Discovery (Handbook of Experimental Pharmacology #281)
Par Markus H. Kuehn, Wei Zhu. 2023
Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given…
rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.Psychophysiology Methods (Neuromethods #206)
Par Massimiliano Valeriani, Marina De Tommaso. 2024
This volume looks at the latest advancements used by researchers to study psychophysiology and cognitive neurosciences. The chapters in this…
book cover topics such as classical event-related brain responses (P300, MMN, and CNV); anatomical structures and physiological mechanisms underlying the capability of feeling pain and smelling; magnetoencephalography (MEG); and brain-computer interface techniques using electrical activity generated by the brain. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Psychophysiology Methods is a valuable resource for researchers who want to learn more about the use of psychophysiological techniques in the investigation of human cognition, and increase interest in the clinical puzzle of neurological and psychiatric disorders.Fear Extinction: From Basic Neuroscience to Clinical Implications (Current Topics in Behavioral Neurosciences #64)
Par Mohammed R. Milad, Seth D. Norrholm. 2023
This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not…
to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone’s life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears. The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.