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Retinal and Choroidal Manifestations of Selected Systemic Diseases
Par J. Fernando Arévalo. 2001
This text presents current information on retinal and choroidal manifestations of systemic diseases from leading experts in the field. Topics…
include retinal and choroidal manifestations of AIDS, pediatric diseases, toxicity of systemic drugs, diseases of the gastrointestinal tract, diffuse unilateral subacute neuroretinitis (DUSN), viral and fungal diseases, sarcoidosis, Behçet's disease, carotid artery and renal diseases, changes related to pregnancy, intraocular lymphoma, and more. Their knowledge and experience will assist ophthalmologists, retina specialists, uveitis and ocular oncology specialists, and general physicians approach a level of knowledge about retinal and choroidal manifestations of systemic diseases to benefit patients in everyday clinical practice.Ocular Blood Flow
Par Leopold Schmetterer, Jeffrey Kiel. 2012
Adequate blood supply to the eye is an important prerequisite for normal visual function. Over the past 40 years our…
knowledge of ocular blood flow regulation has improved significantly. This reader-friendly textbook provides a comprehensive overview of the current knowledge of ocular blood flow. Lavishly illustrated, it evaluates the wide array of methods that have been used to measure ocular blood flow. Furthermore, it not only offers the reader an evidence-based summary of the physiological and pharmacological properties of ocular blood flow regulation, but also demonstrates the ocular blood flow abnormalities in different vascular diseases. This book will enhance the understanding of all who are interested in learning more about ocular blood flow in health and disease.Retinal Degeneration
Par Bernhard H.F. Weber, Thomas Langmann. 2013
Over the past decades, knowledge about the cellular and molecular basis underlying the visual process has remarkably increased. In Retinal…
Degeneration: Methods and Protocols, expert researchers in the field provide a guide of relevant and state-of-the-art methods for studying retinal homeostasis and disease. These include methods and techniques for addressing cell culture systems and animal models of disease, their generation, their phenotypic and molecular characterization as well as their use in therapeutic approaches to the retina. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Retinal Degeneration: Methods and Protocols aids scientists in continuing to study the cutting-edge techniques of retinal cell biology in health and disease.All about Your Eyes
Par Jennifer S. Weizer, Sharon Fekrat. 2006
A concise, easy-to-understand reference book, All about Your Eyes tells you what you need to know to care for your…
eyes and what to expect from your eye doctor.In this reliable guide, leading eye care experts:--explain how healthy eyes work--describe various eye diseases, including pink eye, cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy--provide up-to-date information on eye surgery, including refractive, laser, and cosmeticFor each eye problem, the authors describe in simple, straightforward language--what it is--the symptoms--what, if anything, you can do to prevent it--when to call the doctor--the treatment--the likelihood of recoveryAll about Your Eyes includes a glossary of technical terms and, following each entry, links to web sites where further information may be found.Despite a plethora of scientific literature devoted to vision research and the trend toward integrative research the borders between…
disciplines remain a practical difficulty To address this problem this book provides a systematic and comprehensive overview of vision from various perspectives ranging from neuroscience to cognition and from computational principles to engineering developments It is written by leading international researchers in the field with an emphasis on linking multiple disciplines and the impact such synergy can lead to in terms of both scientific breakthroughs and technology innovations It is aimed at active researchers and interested scientists and engineers in related fieldsCataract Blindness and Simulation-Based Training for Cataract Surgeons: An Assessment of the HelpMeSee Approach
Par Jianhui Hu, Peter Glick, James R. Broyles, Yee-Wei Lim. 2012
Cataracts cause about half of all cases of blindness worldwide, largely in developing countries. HelpMeSee Inc. is developing a simulator-based…
method for rapid cataract surgical training that RAND researchers determined could significantly help to close the backlog of cataract cases, expected to be 32 million globally by 2020. For this to occur, challenges in the areas of outreach, quality monitoring, and public acceptance must be met.Ocular Transporters in Ophthalmic Diseases and Drug Delivery
Par Colin J. Barnstable, Joyce Tombran-Tink. 2008
In this exceptionally important new work, a panel of distinguished authors discusses all the latest developments in the study of…
ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.Vision Research Protocols
Par P. Elizabeth Rakoczy. 2001
Elizabeth Rakcozy and a team of leading clinical and experimental scientists describe in step-by-step detail the key techniques essential to…
effective molecular biological research in ophthalmology and optometry. These readily reproducible methods are adapted to the special requirements of vision research, with coverage that ranges from the most basic to the most sophisticated technologies. Included are methods for the down-regulation of gene expression, new gene therapy techniques, and for the development of transgenic and knockout animal models for testing novel therapies. Eminently accessible and clinically relevant, Vision Research Protocols provides experimental and biomedical investigators in ophthalmology and optometry with a rich panoply of most powerful tools with which to ask--and answer--all the important questions emerging from the dramatically advancing work in vision research today.Studies on Retinal and Choroidal Disorders
Par Thomas W. Gardner, Robert D. Stratton, William W. Hauswirth. 1984
Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and…
pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. It examines the anti-apoptotic activity of α-crystallins in the presence of glutathione, oxidative stress in the mitochondria and endoplasmic reticulum, the role of iron in retinal disease, the mechanisms of pathological VEGF expression, NAPDH oxidase mechanisms, and Hepatocyte Growth Factor in oxidative stress in the retina. A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGF induced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive.Visual Dysfunction in Diabetes
Par Colin J. Barnstable, Joyce Tombran-Tink, Thomas W. Gardner. 2012
An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement is designed with…
two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye. With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic retinopathy are to be found and applied. Developed by a renowned group of authorities, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers responses and context for a range of questions, such as: do metabolic factors beyond glucose contribute to vision-threatening diabetic retinopathy? If so, how do these lead to vision impairment? Is diabetic retinopathy a response to systemic metabolic abnormalities or are there unique ocular problems related to insulin resistance? What is the relationship between the neural, vascular, and inflammatory abnormalities in diabetic retinopathy? Do they represent a pathological cascade induced sequentially or simultaneous responses to one or more metabolic perturbations? The authors note that if we do not address these types of questions, it is possible that the long process of developing new therapeutics will target only one arm of the pathology and leave the retina open to damaging consequences of the others. State-of-the-art, comprehensive, and an invaluable addition the research and clinical literature, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers guidance and a significant step toward new scientific approaches that can lessen the devastating vision impairment associated with diabetes.Herpes Simplex Virus Epithelial Keratitis
Par Helena M. Tabery. 2010
This book on Herpes Simplex Virus Epithelial Keratitis shows a kind of 'living histology', revealing both morphological and dynamic features…
of the disease, and explaining mechanisms behind them. It offers great insights helpful for the differential diagnostics and the recognition of less known variants as well as of complications. It is also highly useful for the follow-up of treatment results and the differentiation between an active infection and sequelae. Thus, this book will be an invaluable aid for ophthalmologists and researchers working with ocular surface diseases.The Male Patient in Aesthetic Medicine
Par Berthold Rzany, Mauricio De Maio. 2009
The demand for cosmetic procedures by male patients has increased in recent years. With this trend has come the realization…
that male aesthetic needs are different from female aesthetic needs. This book is the first hands-on guide dedicated exclusively to the aesthetic treatment of the male patient, and provides cosmetic surgeons with important information on how to obtain a natural male look for such patients. It explains facial aesthetics and the aging process in men, as well as the current aesthetic medicine techniques available. It also offers valuable strategies for avoiding and treating undesired results. Written by internationally known experts in the field, this unique guide enables cosmetic surgeons to achieve the best possible treatment outcomes, as well as increased satisfaction in male patients.Vitreous
Par J. Sebag. 2014
The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There…
have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag's first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspectives in a manner that lends richness to the scope of the book. Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag's latest tome on vitreous is destined to be the authoritative text for years to come.Uveitis
Par George N. Papaliodis. 2017
Uveitis is a practical guide for the diagnosis and treatment of uveitis and ocular inflammatory diseases. This text provides uveitis…
specialists, practicing ophthalmologists, and ophthalmology residents with the appropriate diagnostic testing and evidenced-based therapeutic options for managing patients afflicted with these conditions. The realm of ocular inflammatory diseases is constantly changing with improved diagnostic modalities and treatment options, however, despite these innovations, the ocular inflammatory diseases, including uveitis, are the third leading cause of blindness worldwide. Written and edited by leaders in the fields of ophthalmology, rheumatology, internal medicine, infectious disease, and oncology, Uveitis addresses the latest advances in the field, from the advent of PCR technology, intraocular depot steroid implants, neoplastic and infectious diseases masquerading as uveitis, and the use of systemic immunomoduatory therapies (including biologic agents/humanized monoclonal antibodies in the armamentarium).Small-Gauge Vitrectomy for Diabetic Retinopathy
Par Ulrich Spandau, Zoran Tomic. 2015
This book describes step by step how to operate on the patient with diabetic retinopathy. After thorough explanation of surgical…
planning, including the potential need to perform individual procedures at different time points, each stage of the vitrectomy is clearly documented with the aid of color photographs and drawings as well as online surgical videos. Variations in approach are described that are potentially of value, depending on whether one is dealing with a straightforward diabetic retinopathy or a difficult case of tractional retinal detachment. In the second part of the book, a series of case reports are presented that illustrate the surgical procedures applicable in different circumstances. In addition, pearls and pitfalls are highlighted. Small-Gauge Vitrectomy for Diabetic Retinopathy will be an ideal source of information and guidance for all who are embarking upon such surgery or wish to further hone their skills.Glaucoma Imaging
Par Antonio Ferreras. 2016
This atlas offers a truly comprehensive update on the use of imaging technologies for the diagnosis and follow-up of glaucoma.…
In addition to standard automated perimetry, gonioscopy, fundus photography, and stereophotography, other advanced, high-resolution methods for imaging the eye in glaucoma are explained in detail, including ultrasound biomicroscopy, confocal scanning laser ophthalmoscopy, scanning laser polarimetry, and spectral domain optical coherence tomography. The role of the various tests and the keys to optimizing their use in clinical practice are detailed with the aid of high-quality figures in order to enable the reader to achieve the best possible performance when applying these tools. The risk of developing visual disability and blindness as a consequence of glaucoma varies widely among affected individuals. Personalized testing strategies and tailored therapeutic interventions are required to effectively reduce visual impairment due to glaucoma. Glaucoma Imaging will assist residents, researchers, and clinicians in improving their ability to understand and integrate the information obtained using traditional techniques with the reports provided by computer-assisted image instruments.Pathologic Myopia
Par Richard F. Spaide, Kyoko Ohno-Matsui, Lawrence A. Yannuzzi. 2014
Pathological Myopia is a major cause of severe vision loss worldwide. The mechanisms for vision loss include cataract, glaucoma, retinal…
detachment, and above all, degeneration of the macula within the posterior staphyloma. Pathological Myopia is one of the only current books to specifically address this disease and discusses recent developments in imaging technologies and various approaches to treatments, such as laser photocoagulation, photodynamic therapy, pharmaco-therapeutic injections in the vitreous, and surgery. Complete with high-quality color images, this book is written and edited by leaders in the field and is geared towards ophthalmologists, including residents and fellows in training, glaucoma and cataract specialists, and vitreoretinal macula experts.Orbital Fractures
Par Vadim P. Nikolaenko, Yury S. Astakhov. 2015
This book thoroughly reviews the diagnosis and treatment of injuries of the orbital walls and apex, including orbital floor, medial…
orbital wall, naso-orbito-ethmoid, orbitozygomatic, maxillary, and frontobasilar fractures. For each form of injury, signs and symptoms are identified and clear guidance is provided on the interpretation of clinical and radiological findings and on current surgical treatment methods. In addition, the role of orbital imaging techniques, including CT and MRI, in depicting anatomic relations is explained with the aid of a wealth of radiological images and photographs. The described approach to fracture management is multidisciplinary in nature and the advice is evidence based, drawing on the latest published data. Orbital Fractures: A Physician's Manual will be an invaluable reference and guide for ophthalmologists, maxillofacial surgeons, neurosurgeons, otolaryngologists, radiologists, and emergency physicians. It will also be an excellent resource for all medical students, residents in ophthalmology, and fellows who wish to broaden their spectrum of knowledge in orbital pathology.Managing Complications in Glaucoma Surgery
Par Francis Carbonaro, K. Sheng Lim. 2017
This well-illustrated book is intended as the go-to guide for the identification and management of the complications associated with specific…
glaucoma procedures. All of the routinely performed procedures are covered: filtration surgery, including trabeculectomy and ExPRESS shunt, nonpenetrating surgeries such as deep sclerectomy and canaloplasty, procedures involving the placement of tube shunt devices, glaucoma laser treatments, and minimally invasive glaucoma surgeries (MIGS). The book is succinct but sufficiently detailed to provide the reader with a very well informed description of possible complications and the best way to manage them, based on the evidence from recent and seminal research. The authors are recognized experts who come from a wide geographic and varied glaucoma background. The book will be ideal for all surgeons, whether new or experienced, who seek easily accessible, reliable guidance on how to manage the intraoperative and early and late postoperative complications that may arise when performing glaucoma surgery.Keratoconjunctivitis Sicca and Filamentary Keratopathy
Par Helena M. Tabery. 2011
This book presents in vivo captured high-magnification images of two conditions: keratoconjunctivitis sicca (KCS, or dry eye), an extremely common…
disease of the ocular surface, and filamentary keratopathy, a relatively rare phenomenon most commonly associated with KCS. The images of KCS represent the broad spectrum of ocular surface changes seen in the condition while the images of filamentary keratopathy clearly reveal the components of the ocular surface appendices, termed filaments. The photographs show phenomena captured in various illumination modes, without staining and after staining with diagnostic dyes, and the photographic sequences illustrate their dynamics. The images reflect the in vivo situation. Once aware of the various phenomena, anyone working with standard diagnostic equipment - the slit lamp and the diagnostic dyes- will be able to detect almost all of them. The book will be invaluable for all who deal with ocular surface diseases.